PURPOSE To examine the impact of prolonged graphomotor tasks on tripod-pinch strength and on handwriting process and product measures of children with dysgraphia and typical peers. METHOD Participants were 51 children in third to fifth grades, divided into two groups: 23 children with dysgraphia and 28 typical peers, as determined by the Handwriting Proficiency Screening Questionnaire. The pr...

Cells attach to the extracellular matrix (ECM) through integrins to form focal adhesion complexes, and this process is followed by the extension of lamellipodia to enable cell spreading. PINCH-1, an adaptor protein essential for the regulation of cell-ECM adhesion, consists of five tandem LIM domains and a small C-terminal region. PINCH-1 is known to interact with integrin-linked kinase (ILK) a...

BACKGROUND Carpal tunnel syndrome (CTS) compromises fine sensorimotor function during activities of daily living. Reach-to-pinch for a small object requires not only dexterity of the grasping digits, but also coordinated transport of the hand to the target. This study examined the effects of CTS on the kinematic performance of reach-to-pinch maneuver. METHODS Eleven CTS subjects and 11 able-b...

We have previously found [J. Eggers, M. A. Fontelos, D. Leppinen, and J. H. Snoeijer, Phys. Rev. Lett., 98 (2007), 094502] that the pinch-off of a gas bubble in an inviscid environment is controlled by scaling exponents which are slowly varying in time. To leading order, these results did not require the spatial profile of the interface near break-up. Here we refine our previous analysis by com...

Supply chain managers are trying to maximize the profitable operation of their manufacturing and distribution supply chain, but due to global competition in process industries and complexities of the supply chain processes together with large computational times, it has made optimization of supply chain management (SCM) quite difficult. Recently, Knowledge management (KM) is a new important inf...

This paper contains a linear analysis of pulse shapes produced by a spatial and temporal delta-function disturbance of cyclotron-resonance-maser modes for the case where the initial equilibrium state is free of radiation. A pinch-point analysis based on the theory of Briggs and Bers is employed. Numerical and analytical techniques are developed for the straightforward calculation of pinch-point...