Age related macular degeneration (AMD) is a common disease. Angiography with fluorescein and indocyanine green (ICG) respectively is a proven diagnostic tool, which enables to diagnose the disease's different forms. Being an invasive method, it must however be undertaken with clear indications. This overview article is based on the literature available and on own experiences with exudative AMD,...

This paper describes bilateral tears of the retinal pigment epithelium (RPE) which followed photocoagulation treatment of retinal pigment epithelial detachment (PED) in the right eye and which occurred spontaneously in the left eye. A 66-year-old Japanese male presented with PED approximately 4 X 6 disc diameters in size in his right eye, and one disc diameter in the left eye, both in the macul...

Assessment of serous retinal detachment plays an important role in the diagnosis of central serous chorioretinopathy (CSC). In this paper, we propose an automatic, three-dimensional segmentation method to detect both neurosensory retinal detachment (NRD) and pigment epithelial detachment (PED) in spectral domain optical coherence tomography (SD-OCT) images. The proposed method involves construc...

Proliferative vitreoretinopathy (PVR) is a serious complication of retinal detachment and ocular trauma, and its recurrence may lead to irreversible vision loss. Epithelial to mesenchymal transition (EMT) of retinal pigment epithelial (RPE) cells is a critical step in the pathogenesis of PVR, which is characterized by fibrotic membrane formation and traction retinal detachment. In this study, w...

Purpose To investigate the association between baseline retinal microstructures observed with spectral-domain optical coherence tomography (OCT) and the need for early intervention in central serous chorioretinopathy (CSC). Methods Cases of acute CSC from July 2011 to December 2014 were retrospectively reviewed. OCT images were further classified using six parameters: foveal serous retinal de...

BACKGROUND The purpose of this open-label study was to investigate the effect of a curcumin-phospholipid (lecithin, Meriva(®)) formulation (Norflo(®) tablet) on visual acuity and retinal thickness in patients with acute or chronic central serous chorioretinopathy. METHODS Visual acuity was assessed by ophthalmologic evaluation, and optical coherence tomography was used to measure retinal thic...