The kidneys of a 3-month-old female cat were examined. The cat which had been raised under controlled conditions with no history of any poisoning showed progressive weight loss with increases in blood BUN and creatinine concentrations. At necropsy, both kidneys were firm in consistency with formation of focal scars. Histopathologically, widespread deposition of crystals was observed in the rena...

An unusual case of angiolymphoid hyperplasia with eosinophilia (ALHE) simulating port-wine stain in a 50-year-old woman is reported. The lesions of ALHE are typically papules or subcutaneous masses that range from light pink to red-brown in color. In addition to the usual histologic findings of ALHE, the biopsy in our patient showed some fibrin-like material and fibrous long-spacing collagen on...

BACKGROUND Currently available injectable fillers have demonstrated limited durability. This report proposes the in vitro culture of human adipose-derived stem cells (hASCs) on hyaluronic acid (HA) gel for in vivo growth of de novo adipose tissue. METHODS For in vitro studies, hASCs were isolated from human adipose tissue and were confirmed by multi-lineage differentiation and flow cytometry....

Melioidosis is a significant cause of morbidity and mortality in east Asia and northern Australia (8). Early diagnosis is vital if patients are to receive effective treatment. Definitive laboratory diagnosis is based on the isolation of Burkholderia pseudomallei, but culture is often slow or not available in these regions. Techniques such as direct immunofluorescence (DIF) (9) and urinary antig...

There exist many methods for the application of the Gram stain to histological sections, and with all of them there is generally no difficulty in recognising Gram-positive organisms. However, with most of the well-recognised methods Gram-negative bacteria are difficult to distinguish from the background. Twort's method distinguishes Gram-negative bacteria from the background but is relatively t...

X-34, a lipophilic, highly fluorescent derivative of Congo red, was examined as a histochemical stain for pathological changes in Alzheimer's disease (AD). X-34 intensely stained neuritic and diffuse plaques, neurofibrillary tangles (NFTs), neuropil threads, and cerebrovascular amyloid. Comparison to standard methods of demonstrating AD pathology showed that X-34 correlated well with Bielschows...