A novel fluorescence resonance energy transfer (FRET) system containing a two-photon absorbing dye and a nile red chromophore has been synthesized. Upon two-photon excitation by laser at 815 nm this molecule displays efficient energy transfer from the two-photon absorbing dye to the nile red moiety, with an 8-fold increase in emission compared to the model compound. Similarly, single-photon exc...

BACKGROUND Biophoton emission is the spontaneous emission of ultraweak light emanating from all living systems, including man. The emission is linked to the endogenous production of excited states within the living system. The detection and characterisation of human biophoton emission has led to suggestions that it has potential future applications in medicine. OBJECTIVES An overview is prese...

A filtered backprojection reconstruction algorithm was developed for cardiac single photon emission computed tomography with cone-beam geometry. The algorithm reconstructs cone-beam projections collected from ;short scan' acquisitions of a detector traversing a noncircular planar orbit. Since the algorithm does not correct for photon attenuation, it is designed to reconstruct data collected ove...

This paper discusses the use of small pixels in a spinning CdZnTe single photon emission computed tomography (SPECT) camera that is mounted with a parallel slat collimator. In a conventional slat collimation configuration, there is a detector pixel between two adjacent collimator slats. In our design, the pixel size is halved. That is, there are two smaller pixels to replace a regular pixel bet...

OBJECTIVE This paper explores the importance of the latent symmetry of the brain in computer-aided systems for diagnosing Alzheimer's disease (AD). Symmetry and asymmetry are studied from two points of view: (i) the development of an effective classifier within the scope of machine learning techniques, and (ii) the assessment of its relevance to the AD diagnosis in the early stages of the disea...

BACKGROUND Asymptomatic patients with severe coronary atherosclerosis may have a normal resting electrocardiogram and stress test. AIM To assess the yield of Gated Single Photon Emission Computer Tomography (SPECT) for the screening of silent myocardial ischemia in type 2 diabetic patients. MATERIAL AND METHODS Electrocardiogram, stress test and gated-SPECT were performed on 102 type 2 diab...