On the canalicular membranes of hepatocytes, several ABC transporters are responsible for the secretion of bile lipids. Among them, ABCB4, also called MDR3, is essential for the secretion of phospholipids from hepatocytes into bile. The biliary phospholipids are associated with bile salts and cholesterol in mixed micelles, thereby reducing the detergent activity and cytotoxicity of bile salts a...

In order to determine the feasibility of using radioactive precursors as markers for membrane phospholipids in Acanthamoeba palestinensis, the characteristics of phospholipids labeled with choline-14 C and glycerol-3H were examined . Choline-14 C was found to be a specific label for phosphatidyl choline . There was a turnover of the radioactive moiety of phosphatidyl choline at a rate that vari...

In this review paper, the latest literature on the functional properties of phospholipids in relation to inflammation and inflammation-related disorders has been critically appraised and evaluated. The paper is divided into three sections: Section 1 presents an overview of the relationship between structures and biological activities (pro-inflammatory or anti-inflammatory) of several phospholip...

Abstract To explore energy utilization during molting stage, matured and juvenile red claw crayfish were selected to determine changes in lipid composition fatty acid contents of hepatopancreas. Moreover, the expression binding protein (FABP) gene was determined verify acids at molecular level. Results showed that after molting, crude content significantly lower than before ( p <.05). Among ...

For a multiproduct microalgal biorefinery, most of the cell components should be extracted and fractionated. This work investigates fractionation lipids from other (pigments, proteins, carbohydrates) using polymers IL solutions in aqueous two-phase systems (ATPS). The poorly migrated to phases ATPS were recovered (97% total fatty acids) third phase (interphase) formed between top bottom phases....

The proliferative-crypt compartment of the intestinal epithelium is enriched in phospholipids and accumulation of phospholipids has been described in colorectal tumors. Here we hypothesize that biliary phospholipid flow could directly contribute to the proliferative power of normal and dysplastic enterocytes. We used Abcb4-/- mice which lack biliary phospholipid secretion. We first show that Ab...

Dairy byproducts represent a rich source of phospholipids with the potential for isolation and further commercialization. In this study, we extracted from two dairy (buttermilk beta-serum) using tertiary amine (N,N-dimethylcyclohexylamine, CyNMe2) as switchable hydrophilicity solvent. For comparison, were via Folch (chloroform: methanol). CyNMe2 extraction resulted in recovery values 98.66 ± 0....

Previous studies on human serum phospholipids have dealt with concentration in whole serum (l-3). With the introduction of the concept of lipoproteins (4) and lipoprotein classes (5) it became of interest to study the phospholipids of serum as structural units of these macromolecules. Whereas there is now agreement on the relative proportions of the phospholipid species in whole serum, it has n...

Previous studies on human serum phospholipids have dealt with concentration in whole serum (l-3). With the introduction of the concept of lipoproteins (4) and lipoprotein classes (5) it became of interest to study the phospholipids of serum as structural units of these macromolecules. Whereas there is now agreement on the relative proportions of the phospholipid species in whole serum, it has n...

found in the response of the electron-capture detector for fatty acids of niicrosomal lipids from CC1,-treated rats (the latter peak is clearly a group of unresolved peaks). Since serum very-low-density lipoproteins derive directly from the hepatic cell and since the phospholipid fraction of such lipoproteins is believed to derive from the phospholipids of the endoplasmic reticulum, we investig...