An algorithm is being presented for a special class of unconstrained minimization problems. The algorithm exploits the special structure of the Hessian in the problems under consideration, It is based on applying Bertsekas' I-1] Scaled Partial Conjugate Gradient method with respect to a metric that is updated by the Rank One update, using gradients obtained in the preceeding steps. Two classes ...

A novel stability-indicating gradient reverse phase liquid chromatographic method was developed for the quantitative determination of process related impurities and forced degradation products of Dipyridamole in Dipyridamole retard capsules. This method is able separate all seven known impurities which includes two newly identified potential degradant impurities.The method was developed by usin...

in this paper a fast and novel stability-indicating ultra fast lc method for separation and estimation of impurities in clopidogrel and aspirin in their combined tablet dosage form and omeprazole was developed. the separation of usp related substances of clopidogrel (a, b and c), aspirin (d), omeprazole (a, b and c) and few other unknown impurities was detected by using ultra fast liquid chroma...

Article history: Received 01 July 2015 Accepted 29 July 2015 In the present study, simple and reliable method of histamine analysis was developed, optimized and validated to meet the requirements of fish safety. Histamine in fish samples was extracted with a methanol–phosphate buffer including 2 % TCA solution (50:50, v/v) followed by defatting with hexane after centrifugation at 13,000 rpm. Hi...

BACKGROUND/AIMS Excessive phosphate concentrations trigger vascular calcification, an active process promoted by osteoinduction of vascular smooth muscle cells (VSMCs) with increased expression and activity of transcription factor RUNX2 (Core-binding factor α1, CBFA1), alkaline phosphatase (ALPL), TGFß1, transcription factor NFAT5, and NFAT5-sensitive transcription factor SOX9. The osteoinducti...

Partial least squares modeling as a powerful multivariate statistical tool was applied tothe simultaneous spectrophotometric determination of silicate and phosphate in aqueoussolutions. The concentration range for silicate and phosphate were 0.02-0.6 and 0.4-3 μg ml-1,respectively. The experimental calibration set was composed with 30 sample solutions using amixture design for two component mix...

In this article, the effect of potassium on structure and anticorrosion properties of zinc phosphate pigments has been investigated. The co-precipitation method was selected as synthesis method of potassium zinc phosphate pigment. Then the synthesized pigment was characterized by x-ray diffraction XRD, Fourier transform infrared FTIR and Raman spectroscopy. Morphology of the powders was investi...

Sensitivity analysis on Sea Surface Temperature: SST estimation with Thermal Infrared Radiometer: TIR data through simulations is conducted. Also Conjugate Gradient Method: CGM based SST estimation method is proposed. SST estimation error of the proposed CGM based method is compared to the conventional Split Window Method: SWM with a variety of conditions including atmospheric models. The resul...

In conjugate gradient method, it is well known that the recursively computed residual differs from true one as the iteration proceeds in finite arithmetic. Some work have been devoted to analyze this be-havior and to evaluate the lower and the upper bounds of the difference. This paper focuses on the behavior of these two kinds of residuals, especially their lower bounds caused by the loss of t...