A highly efficient copper-catalyzed system using commercially available racemic 1,1′-binaphthyl-2,2′-diol (rac-BINOL) as the ligand was eveloped for amination of aryl halides and heteroaryl halides with alkyl amines and N H heterocycles. Good to high yields were obtained for aryl romides and heteroaryl chlorides. The commercially available rac-BINOL ligand with excellent stability and high effi...

A one-pot, convenient method for the preparation of optically active homoallylic alcohols from allyl halides was developed. Allyltrichlorosilanes were generated in situ from allyl halides and trichlorosilane in the presence of cuprous chloride and tertiary amine. Without isolation of the allyltrichlorosilanes, benzaldehyde and chiral biquinoline N,N'-dioxide were introduced into the same flask,...

In this study, a one-pot and efficient method is reported for the synthesis of symmetrical disulfides from alkyl halides in the present of sulfur and 1-butyl-3-methylimidazolium hydroxide as a basic reagent and phase transfer catalyst. The reaction proceeded very fast and afforded the desired products in moderate to excellent isolated yields.

Some N¬-acyl-N'-aryl thiourea derivatives 4(a-f) have been prepared by the reaction of acyl halides ammonium thiocyanate and aryl amines. The structures of synthesized compounds have been characterized by IR, 1HNMR spectral studies. The synthesized compounds 5(a-f) have been screened for antibacterial activity. The effect of the structure of the investigated compounds on the antibacterial activ...

a simple, mild and practical procedure has been developed for the synthesis of symmetrical and unsymmetrical ethers by using dmso, tbai in the presence of k2co3. we extended the utility of  potassium carbonate as an efficient base for the preparation of ethers. a wide range of alkyl aryl and dialkyl ethers are synthesized from treatment of aliphatic alcohols and phenols with various alkyl halid...

Synthesis and characterization of new thiadiazoles, bisthiadiazoles from the reaction of mono- and di-hydrazonoyl halides with various hydrazinecarbodithioate derivatives were studied. Treatment of hydrazonoyl halides with 2,5-dihydrazinyl-1,3,4-thiadiazole afforded new bistriazines containing thiadiazole; we also examined the reaction of 2,5-dihydrazinyl-1,3,4-thiadiazole with active methylene...

The formation of the textures on the surface of the films from the solutions of bovine serum albumin (BSA) with sodium halides (NaF, NaCl, and NaBr) of various concentrations was studied. The formation of symmetric zigzag textures on the surface of BSA films (Cryst Eng 3:173-194, 2000) in the presence of sodium halides depends on the conformational state of the protein globule. Thermal denatura...

An investigation was undertaken to study the factors which cause grossly elevated values in an automated procedure for chloride when the sample is contaminated with bromide. The questioned mercuric thiocyanate method of the autoanalyzer was compared to a similar system utilizing mercuric 2, 4, 6-tripyridyl-s-triazine as a substitute ligand source in the chloride exchange system. It was determin...

In group-III nitrides in use for white light-emitting diodes (LEDs), optical gain, measure of luminous efficiency, is very low owing to the built-in electrostatic fields, low exciton binding energy, and high-density misfit dislocations due to lattice-mismatched substrates. Cuprous halides I-VII semiconductors, on the other hand, have negligible built-in field, large exciton binding energies and...