نتایج جستجو برای: pharmacological sample

تعداد نتایج: 480575  

2015
Jonathan A Cook Jenni Hislop Douglas G Altman Peter Fayers Andrew H Briggs Craig R Ramsay John D Norrie Ian M Harvey Brian Buckley Dean Fergusson Ian Ford Luke D Vale

BACKGROUND Central to the design of a randomised controlled trial is the calculation of the number of participants needed. This is typically achieved by specifying a target difference and calculating the corresponding sample size, which provides reassurance that the trial will have the required statistical power (at the planned statistical significance level) to identify whether a difference of...

Journal: :Statistics in medicine 1998
F Y Hsieh D A Bloch M D Larsen

A sample size calculation for logistic regression involves complicated formulae. This paper suggests use of sample size formulae for comparing means or for comparing proportions in order to calculate the required sample size for a simple logistic regression model. One can then adjust the required sample size for a multiple logistic regression model by a variance inflation factor. This method re...

Journal: :Controlled clinical trials 2003
Roger P Qu Hongjie Zheng

Exact power and sample size calculation for bioequivalence studies with high order crossover designs using statistical software nQuery are presented. Such calculation can be very easily performed, and thus provides a convenient tool for practical usage.

Journal: :JACC: Cardiovascular Interventions 2013

Journal: :Postgraduate Medical Journal 1974

Objective: Rose oil is obtained from the petals of difference Rosa species especially Rosa centifolia L. and Rosa damascena Mill. Various pharmacological properties have been attributed to rose oil. The aim of the present study was to review the rose oil therapeutic effects which had been clinically evaluated in trial studies. Materials and Methods: Google scholar, PubMed, Cochrane Library, and...

افخم ابراهیمی, عزیزه , بیرشک, بهروز , زارع, مریم , شایقیان, زینب ,

Objectives: In order to investigate the effectiveness of pharmacological and non-pharmacological treatment methods for decreasing agitation in diseases like dementia, a proper scale like Cohen-Mansfield Agitation Inventory (CMAI) is needed. The aim of the present study was to evaluate the psychometric properties of the CMAI. Method: The sample consisted of 100 caregivers of patients with Alzhei...

Journal: :Journal of biopharmaceutical statistics 2005
Hansheng Wang Shein-Chung Chow Murphy Chen

In clinical research, parameters required for sample size calculation are usually unknown. A typical approach is to use estimates from some pilot studies as the true parameters in the calculation. This approach, however, does not take into consideration sampling error. Thus, the resulting sample size could be misleading if the sampling error is substantial. As an alternative, we suggest a Bayes...

Journal: :Proceedings of the Royal Society of Medicine 1927

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