نتایج جستجو برای: pharmaceutical tablets
تعداد نتایج: 77375 فیلتر نتایج به سال:
Background: Repackaging tablets into a dose administration aid (DAA) requires that the pharmacist consider the stability of the active pharmaceutical ingredient and the excipients of the drug product. Frusemide is susceptible to photodegradation and is commonly repackaged into DAAs. Aim: To evaluate the stability (chemical and physical) of frusemide tablets repackaged into DAAs. Method: Frusemi...
In this study near-infrared (NIR) transmission and diffuse reflection spectra of tablets with two different pharmaceutical active substances in variable concentrations were recorded. The purpose of these tests was to correlate the spectra with the content of active ingredient, hardness and moisture content in order to implement a fast, non-destructive quality control of solid drug formulations ...
Amlodipine is a dihydropyridine drug that used to lower high blood pressure. In this study, the photostabilities of orally disintegrating (OD) amlodipine tablets, both original and generic versions, their powdered suspended forms were evaluated. The concentration active pharmaceutical ingredient (API) was monitored by high-performance liquid chromatography (HPLC), revealing residual amounts API...
In this study, simple, fast and reliable cyclic voltammetry (CV), linear sweep voltammetry (LSV), square wave voltammetry (SWV) and differential pulse voltammetry (DPV) methods were developed and validated for determination of bosentan in pharmaceutical preparations. The proposed methods were based on electrochemical oxidation of bosentan at platinum electrode in acetonitrile solution containin...
Tablets containing metoprolol succinate and Compritol(®) 888ATO in the ratio of 1:2 yielded the desired sustained release profile in phosphate buffer pH 6.8 when evaluated using USP type II paddle apparatus and was selected as the optimized formulation. Robustness of optimized formulation was assessed by studying the effect of factors like varying source of metoprolol succinate and Compritol(®)...
Pharmaceutical companies are manufacturers of both solid and liquid formulations. Solid formulations may be tablets, dry powers, confectionary and solid injectables; liquid formulations may be eye drops, ointments, I.V. and other parenteral solutions. Parenteral solutions are packed as large volume parenteral (LVP) solutions, small volume parenteral (SVP) solutions and dry powders requiring rec...
Three-dimensional (3D) printers have been applied in many fields, including engineering and the medical sciences. In the pharmaceutical field, approval of the first 3D-printed tablet by the U.S. Food and Drug Administration in 2015 has attracted interest in the manufacture of tablets and drugs by 3D printing techniques as a means of delivering tailor-made drugs in the future. In current study, ...
PURPOSE This study describes the development and validation of dissolution tests for fexofenadine hydrochloride capsules and coated tablets using an HPLC method. METHOD The appropriate conditions were determinate after testing sink conditions, dissolution medium, and agitation intensity. The apparatus, paddle and basket, were applied to tablets and capsules, respectively. Fexofenadine hydroch...
Gurpreet Kaur Ranbaxy Research Labs, Gurgaon, India Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala-147002, India Tel: 919814724622 Fax +91-(0175)-3046255 Email: [email protected] Abstract The present study was designed to formulate colon release tablets of fluticasone by employing cross linked chitosan (CH) and carboxymethyl guar gum (CMG) interpolymer comp...
The aim of this study was to develop a derivative of chitosan as pharmaceutical excipient used in sustained-release matrix tablets of poorly soluble drugs. A water-soluble quaternary ammonium carboxymethylchitosan was synthesized by a two-step reaction with carboxymethylchitosan (CMCTS), decylalkyl dimethyl ammonium and epichlorohydrin. The elemental analysis showed that the target product with...
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