internationalization is a matter of committed decision-making that starts with export marketing, in which an organization tries to diagnose and use opportunities in target markets based on realistic evaluation of internal strengths and weaknesses with analysis of macro and microenvironments in order to gain presence in other countries. a developed model for export and international marketing of...

Keyphrases D Pharmaceutical salts-general pharmacy, physicochemical properties, bioavailability, pharmaceutical properties, toxicology, review J:J Salts, pharmaceutical-general pharmacy, physicochemical properties, bioavailability, pharmaceutical properties, toxicology, review J:J Physicochemical properties-dissolution, solubility, stability, and organoleptic properties of pharmaceutical salts,...

The aim of our article was the study current state pharmaceutical market Ukraine in context quality assurance medicines and preventing spread falsified (FM), identification main problems field circulation ways to solve them. It is established that dynamic development its high profitability cause problem drug quality, increasing threats FM require implementation effective mechanisms for regulati...

Mathematical statistics uses two major paradigms, conventional (or frequentist), and Bayesian. Bayesian methods provide a complete paradigm for both statistical inference and decision making under uncertainty. Bayesian methods may be derived from an axiomatic system, and hence provide a general, coherent methodology. Bayesian methods contain as particular cases many of the more often used frequ...

The statistics of drug development output and declining yield of approved medicines has been the subject of many recent reviews. However, assessing research productivity that feeds development is more difficult. Here we utilise an extensive database of structure-activity relationships extracted from papers and patents. We have used this database to analyse published compounds cumulatively linke...

the supply chain represents the critical link between the development of new product and the market in pharmaceutical industry. over the years, improvements made in supply chain operations have focused largely on ways to reduce cost and gain efficiencies in scale. in addition, powerful regulatory and market forces have provided new incentives for pharmaceutical firms to basically rethink the wa...

a simple and rapid stability indicating method based on capillary zone electrophoresis has been developed and validated for the analysis of buserelin (bus). the best separations were achieved by using a bare fused silica capillary (75 m i.d.; 65.5 cm total, 57.0 cm effective length), phosphate buffer (ph = 3.00; 26.4 mm), at 35 °c. the sample was hydrodynamically injected at 50 mbar for 5 seco...

in this study, a new reaction system for quantitative determination of ascorbic acid was introduced. the developed method is based on inhibitory effect of ascorbic acid on the orange g-bromate system. the change in absorbance was followed spectrophotometrically at 478 nm. the dependence of sensitivity on the reaction variables including reagents concentration, temperature and time was investiga...

many recent studies have shown that glycosylation patterns of agaricus bisporus are similar to those of mammalians, so that this organism is a good candidate for the expression of glycosylated pharmaceutical protein. to achieve constant interested gene expression in all cells of the organism, proper promoter isolation is necessary. to isolate this promoter, pcr with specific primers was perform...