Screening for pharmaceutically viable stability from measurements of thermally induced protein unfolding and short-term accelerated stress underpins much molecule design, selection, and formulation in the pharmaceutical biotechnology industry. However, the interrelationships among intrinsic protein conformational stability, thermal denaturation, and pharmaceutical stability are complex. There a...

The effects of magnesium stearate (MgSt) and shear stress on flow properties and hydrophobicity are not well known. Blends with different concentrations of magnesium stearate and varying amounts of shear were tested using three different procedures: the FT4 Rheometer test, a tap density analyzer, and the Washburn method, to better understand the relation of lubricant concentration, amount of sh...

Nonsense mutations underlie about 10% of rare genetic disease cases. They introduce a premature termination codon (PTC) and prevent the formation of full-length protein. Pharmaceutical gentamicin, a mixture of several related aminoglycosides, is a frequently used antibiotic in humans that can induce PTC readthrough and suppress nonsense mutations at high concentrations. However, testing of gent...

Pharmaceutical industry is currently undergoing a transient phase with new orientation. Loss of financial resources, presence of new therapeutic agents and increasing cost of research and development have called for a full.scale restructuring within the pharmaceutical industry to retain even the most basic competitiveness. The development of new technologies has been as one way out of the dile...

funding combination is the most important issue for the companies while they know the amount of required capital. companies should be careful regarding the appliance of financial providing methods compatible with the investment strategy of company and profitability. this study seeks to examine the relationship between the capital structure and the profitability of pharmaceutical companies in ir...

pharmaceutical products prepared in pharmacies have the potential of contamination with different microorganisms. this is in part due to the unhygienic environment and also lack of a suitable preservative system. in this study, microbial quality of eucerin-urea ointments prepared at different pharmacies in tehran, at the point of sale and also after two weeks storage at room temperature was exa...

as global competition intensifies, research and development (r & d) organizations need to enhance their strategic management in order to become goal-directed communities for innovation and allocate their resources consistent with their overall r & d strategy. the world pharmaceutical market has undergone fast, unprecedented, tremendous and complex changes in the last several years. the pharmace...

chamomile is a widely recognized herb in western culture. its medicinal usage dates back to antiquity where such notables as hippocrates, galen, and asclepius made written reference to it. as part of any medication history, pediatricians always should ask a child’s caregiver about the child’s use of over-the-counter remedies and herbal products. chamomile is used widely to treat children who ha...

not all values of literary texts should be sought for in their artistic aspects . there have been many lower-ranked literary texts that have shed light on numerous scientific, historical, social, and cultural issues. although poetic views are involved while raising such issues, it needs to be taken into account that not all poets have perceived the scientific principles of the topics tackled in...

like many other developing countries pharmacoeconomics and outcome research and its applications in national health system is a new but promising filed in iran. although decision makers of iran national health system decided to use pharmacoeconomics in the decision making approach several hurdles including lack of reliable national data, lack of expertise and local experience are the main chall...