Objectives The aim of this study is to examine the effect of different smoothing filters on the image quality and SUVmax to achieve the guideline recommended positron emission tomography (PET) image without harmonization. Methods We used a Biograph mCT PET scanner. A National Electrical Manufacturers Association (NEMA) the International Electrotechnical Commission (IEC) body phantom was fille...

This paper will deal mainly with the performance study and analysis statistical properties of the noise found in various PET images. The method is specifically designed for types of noise produced by acquisition and transmission sequence in PET images. Here signal fluctuations generally originate in the physical processes of imaging rather than in the tissue textures. Various types of noise (tr...

In vivo imaging of amyloid burden with positron emission tomography (PET) provides a means for studying the pathophysiology of Alzheimer's and related diseases. Measurement of subtle changes in amyloid burden requires quantitative analysis of image data. Reliable quantitative analysis of amyloid PET scans acquired at multiple sites and over time requires rigorous standardization of acquisition ...

UNLABELLED Simultaneous PET and MRI using new hybrid PET/MRI systems promises optimal spatial and temporal coregistration of structural, functional, and molecular image data. In a pilot study of 10 patients with intracranial masses, the feasibility of tumor assessment using a PET/MRI system comprising lutetium oxyorthosilicate scintillators coupled to avalanche photodiodes was evaluated, and qu...

UNLABELLED An efficient method for tomographic imaging in nuclear medicine is PET. Higher sensitivity, higher spatial resolution, and more accurate quantification are advantages of PET, in comparison to SPECT. However, a high noise level in the images limits the diagnostic utility of PET. Noise removal in nuclear medicine is traditionally based on the Fourier decomposition of the images. This m...

Nuclear medicine has a long tradition of incorporating quantitative analysis in its diagnostic and therapeutic procedures. Many of the clinical and research applications of molecular imaging rely on a solid quantitative foundation, which is highly dependent on the performance characteristics of nuclear medicine instrumentation and the accuracy of image correction and reconstruction algorithms. ...

In Positron Emission Tomography (PET), an optimal estimate of the radioactivity concentration is obtained from the measured emission data under certain criteria. So far, all the well-known statistical reconstruction algorithms require exactly known system probability matrix a priori, and the quality of such system model largely determines the quality of the reconstructed images. In this paper, ...

PURPOSE PET (positron emission tomography) imaging researches of functional metabolism using fluorodeoxyglucose (18F-FDG) of animal brain are important in neuroscience studies. FDG-PET imaging studies are often performed on groups of rats, so it is desirable to establish an objective voxel-based statistical methodology for group data analysis. MATERIAL AND METHODS This study establishes a sta...

UNLABELLED For quantitative PET information, correction of tissue photon attenuation is mandatory. Generally in conventional PET, the attenuation map is obtained from a transmission scan, which uses a rotating radionuclide source, or from the CT scan in a combined PET/CT scanner. In the case of PET/MRI scanners currently under development, insufficient space for the rotating source exists; the ...

Content-based image retrieval (CBIR) refers to the use of visual features for images retrieval, and has become an attractive approach to managing biomedical image achieves. However, existing CBIR systems are typically designed for 2D single-modality imaging, and are restricted when multi-dimensional images are considered. With the advances in imaging scanners, image complexity and magnitude hav...