BACKGROUND Canine lymphoproliferative disease often presents with lymphocytosis and is immunophenotypically diverse. HYPOTHESIS Immunophenotype predicts prognosis in canine lymphoproliferative disorders involving circulating lymphocytosis. ANIMALS Dogs that had peripheral blood evaluation performed by flow cytometry by the Clinical Immunology Service at Colorado State University between 200...

INTRODUCTION Persistent polyclonal B-cell lymphocytosis is a rare hematological disorder, characterized by a chronic, stable and absolute polyclonal lymphocytosis, the presence of binucleated lymphocytes, a polyclonal increase in serum IgM immunoglobulin and clonal cytogenetic abnormalities involving chromosome 3. For explaining the expansion of B-lymphocytes pool in PPBL, an association with c...

ly. CD158a and b were not expressed by these cells. Natural killer activity was normal. This case report describes an unusual context for the development of persistent NK lymphocytosis, i.e. more than one year post-transplantation, after infectious episodes not unusual in transplantation. This patient differs from the 26 CD8–/CD4–/NKa+ cases reported by Scott et al.,2 since nearly all lymphocyt...

Polyclonal B lymphocytosis was found in four patients having clinical and hematologic features resembling those of hairy cell leukemia (HCL). All four patients were women between 37 and 67 years of age. Three patients had splenomegaly. Lymphadenopthy was absent or slight. Persistent lymphocytosis was seen in all the patients, and anemia and/or thrombopenia was observed in three of the patients....

Diffuse infiltrative lymphocytosis syndrome (DILS) is characterised by a persistent CD8+ lymphocytosis and lymphocytic infiltration of various organs. The reported prevalence varies between 0.85 – 3%, and appears to be more common in Africans. Patients with DILS tend to have higher CD4+ cell counts and survive longer than those patients without DILS. Most patients present with bilateral parotid...

Abstract Bovine leukosis is caused by an oncogenic virus of the genus Deltaretrovirus, causing losses associated with decreased production indicators and restrictions on exports cattle products. The disease has a prolonged incubation period between 1–5 years antibodies can be detected 2–3 weeks post infection. present asymptomatically, develop persistent lymphocytosis or lymphosarcoma. objectiv...

BACKGROUND The proliferation of clonal cytotoxic T-cells or natural killer cells has been observed after dasatinib treatment in small studies of patients with chronic myeloid leukemia (CML). METHODS The incidence of lymphocytosis and its association with response, survival, and side effects were assessed in patients from 3 large clinical trials. Overall, 1402 dasatinib-treated patients with n...

Etude de deux cas d'Hyperlymphocytose in­fectieuse benigne consernant de deux enfants subfebriles, Sans adenopathies ni Hepato-SplenG---­ megalie confirmee par les examens bi.ologiques et en particulier Etude cytologique de la moele osseuse;  Amelioration clinique et Hematologique de fac;on spontanee sans Traitement. 

Peripheral blood lymphocytes from 14 cattle infected with the bovine leukemia virus (BLV) and 14 BLV-free cattle were examined by the membrane immunofluorescent antibody technique to detect surface immunoglobulin (S-Ig) and by the erythrocyte-antibody-complement (EAC) rosette test for the detection of complement receptors. Direct comparisons of the percentages of S-Ig-bearing cells and EAC rose...