The stimulatory effect of ferrous salts on the peroxidation of phospholipids can be enhanced by EDTA when the concentration of Fe2+ in the reaction is greater than that of EDTA. Hydroxyl-radical scavengers do not inhibit peroxidation until the concentrations of Fe2+ and EDTA in the reaction are equal. Lipid peroxidation is then substantially initiated by hydroxyl radicals derived from a Fenton-...

The modulation of radiation induced lipid peroxidation in synaptosomes by iron (II) and iron (III) complexes of two naturally occurring and therapeutically relevant naphthoquinones viz. 5,hydroxy-1,4 naphthoquinone; juglone and 2,hydroxy-1,4 naphthoquinone; lawsone, have been studied. At lower concentrations the complexes enhance lipid peroxidation predominantly through redox cycling as observe...

Ferritin-containing fractions with different degrees of iron loading were prepared. All ferritin fractions stimulated the peroxidation of bovine brain phospholipid liposomes, as measured by the formation of thiobarbituric acid-reactive material. This stimulation was increased in the presence of ascorbate. Iron salts of equivalent concentration to those of the ferritin fractions were more stimul...

1. Cystamine slightly stimulated the peroxidation of lipids in mitochondria. Maximal effects were obtained at low concentrations (0.5mm). 2. Cysteamine, when allowed to autoxidize, had much stronger effects than cystamine. 3. Cysteamine and GSH did not induce peroxidation when their autoxidation was counteracted. 4. When kept reduced, cysteamine prevented the ascorbate-induced peroxidation of l...

objective: oxidative stress is the result of an imbalance between free radical production and antioxidant defenses of the body. the use of antioxidants can have preventive effects in diabetes. the present study aims to show the effects of biarum bovei extracts on lipid profile, lipid peroxidation in streptozocin induced diabetic male rats. materials and methods: animals were randomly assigned t...

background: melatonin is a free radical scavenger. it has also antioxidant effects through its stimulatory actions on antioxidant system. objective: we conducted this study to examine the effect of different oral doses of melatonin on liver tissue. methods: we used 42 rats—6 rats in each group. group i served as the control group; group ii rats were pretreated with only melatonin; group iii was...

reactive oxygen species cause to release of dormancy in many plants such as sunflower seeds. this study investigated in order to evaluation role of reactive oxygen species germination and lipid proxidation in sunflower seeds. this study was performed in two separate experiments, each in a completely randomized design with factorial design with four replications.  in both experiments, uses from ...

background & aim: applications of synthetic antioxidant in food have side effects. in present study, the antioxidant potential of morus alba leaves, as natural antioxidant, was screened with cupric ion reducing assay (cuprac assay) and inhibition of lipid peroxidation. the aim of this study was to determine the total antioxidant activity of morus alba leaves. martial & methods: the fir...

Levels of conjugated dienes of fatty acids (first peroxidation product) in relation to their substrates and promotors (triacylglycerols, homocysteine, iron) as well as to their inhibitors (essential antioxidative vitamins) were assessed in a vegetarian group (n=24) and compared with subjects on a mixed diet (traditional nutrition, n=24). Positive significant linear correlation between conjugate...