background: regulatory t cells (t-regs) have an important role in cancer by suppression of protective antitumor immune responses. regulatory t cells express the forkhead/winged helix transcription factor (foxp3) and ox40 molecules which have important regulatory roles in the immune system. objective: to evaluate foxp3 and ox40 transcripts in the peripheral blood mononuclear cells of women with ...

Endotoxin lipopolysaccharide (LPS) is the most powerful and effective immunostimulant key virulence factor produced by Escherichia coli (E. coli) accountable for many of inflammatory changes observed during bovine mastitis. In this study, whole-transcriptomic gene in peripheral blood mononuclear cells (PBMCs) stimulated with LPS were compared to control group analyzed RNA sequencing. A total 35...

objective: gelatinases are a large group of proteolytic enzymes that belong to the matrix metalloproteinases (mmps). mmps are a broad family of peptidases, which proteolyse the extracellular matrix and have an important role in inflammation. verapamil is a calcium channel blocker extensively used in the treatment of numerous cardiovascular diseases such as arrhythmia and hypertension. the anti-...

this in vitro study was conducted to evaluate lymphocyte blastogenic and cytokine production by bovine peripheral blood mononuclear cells (pbmcs) stimulated with phytohemagglutinin (pha), pokeweed mitogen (pwm) and concanavalin a (con a) mitogens, by using tetrazolium salt and elisa tests, respectively. the results presented that  interleukin-2 (il-2), il-4, il-5, il-10, il-17 and ifn-γ product...

This in vitro study was conducted to evaluate lymphocyte blastogenic and cytokine production by bovine peripheral blood mononuclear cells (PBMCs) stimulated with phytohemagglutinin (PHA), pokeweed mitogen (PWM) and concanavalin A (Con A) mitogens, by using tetrazolium salt and ELISA tests, respectively. The results presented that  Interleukin-2 (IL-2), IL-4, IL-5, IL-10, IL-17 and IFN-...