The science of periodontology has yielded significant insights into this common disease of man. The field of anaerobic microbiology is arguably developed to its current level by periodontal researchers and our treatment strategies are based on our understanding of the infectious nature of the disease. Yet, we are in the midst of a major paradigm shift in periodontology. We have come to understa...

Periodontal ligament stem cells (PDLSCs) are promising cell resource for the cell-based therapy for periodontitis and regeneration of bio-root. In this study, we investigated the effect of PDLSCs on neutrophil, a critical constituent of innate immunity, and the underlying mechanisms. The effect of PDLSCs on the proliferation and apoptosis of resting neutrophils and IL-8 activated neutrophils wa...

Studies have suggested that A. actinomycetemcomitans is involved in the aetiology of aggressive periodontitis as well as in chronic periodontitis. This study was aimed at elucidating the occurrence of A. actinomycetemcomitans in a Brazilian population with chronic periodontitis. A total of 555 (mean age 33.04 +/- 12.45) individuals, living in two large areas of the São Paulo State, namely "Baix...

Periodontal diseases are global health concern since they affect almost 20-50% of population and widespread in both developed developing countries. disease develops as result persistent infection caused by different periodontopathic bacteria inflammation tooth's supporting tissue. Traditional methods periodontal care involve mechanical removal biofilm using antibiotics antibacterial disinfectan...

introduction: deep periodontal pockets pose a great challenge for nonsurgical periodontal treatment. scaling and root planing (srp) alone may not suffice in cases where surgical therapy cannot be undertaken. various recent studies have suggested the use of antimicrobial photodynamic therapy (apdt) for the management of periodontal infections. the aim of this study was to evaluate the effects of...

Purpose: Traditional approaches to mechanical debridement of the tooth surface to remove tooth accretions continue to be an integral part of periodontal therapy. The purpose of the present study was to test the effectiveness of mechanical non-surgical therapy in subjects with moderate to severe gingivitis and periodontitis. Methods: Ten subjects of moderate to severe gingivitis/periodontits wer...

The native periodontium includes cementum, a functionally oriented periodontal ligament, alveolar bone and gingiva. Pathologic and/or traumatic events may lead to the loss or damage of this anatomical structure. Since the 1970s, a number of procedures have been investigated in an attempt to restore such lost tissues. Numerous clinical trials have shown positive outcomes for various reconstructi...

Introduction: Deep periodontal pockets pose a great challenge for nonsurgical periodontal treatment. Scaling and root planing (SRP) alone may not suffice in cases where surgical therapy cannot be undertaken. Various recent studies have suggested the use of antimicrobial Photodynamic Therapy (aPDT) for the management of periodontal infections. The aim of this study was to evaluate the effects of...

BACKGROUND Regenerative techniques help promote the formation of new attachment and bone filling in periodontal defects. However, the dimensions of intraosseous defects are a key determinant of periodontal regeneration outcomes. In this study, we evaluated the efficacy of use of anorganic bovine bone (ABB) graft in combination with collagen membrane (CM), to facilitate healing of noncontained (...

OBJECTIVES The purpose of this systematic review was to determine the efficacy of machine-driven compared with manual subgingival debridement in the treatment of periodontitis. BACKGROUND Mechanical debridement of the periodontal pocket plays a pivotal role in the treatment of periodontitis. METHODS A literature search for controlled clinical trials with at least 6 months' follow-up compari...