INTRODUCTION: Medullary carcinoma is a rare malignant neuroendocrine tumor of the thyroid gland. (MTC) has no specific clinical symptoms. Due to absence symptoms, disease usually diagnosed at stage metastatic lesions regional lymph nodes, and sometimes, internal organs. The five- ten-year survival after detection distant metastases 25% 10%, respectively. OBJECTIVE: To analyze available foreign ...

Iron–sulfur clusters are ubiquitous cofactors that mediate central biological processes. However, despite their long history, these metallocofactors remain challenging to investigate when coordinated small (≤ six amino acids) oligopeptides in aqueous solution. In addition being often unstable vitro, iron–sulfur can be found a wide variety of forms with varied characteristics, which makes it dif...

Insects or products derived from insects are considered as a valuable feed ingredient for aquaculture, poultry, and pigs but also exert possible secondary effects of health stimulators in livestock reported literature. Health benefits attributed to can create additional value the insect chain. Three categories bioactive compounds this desk study: antimicrobial peptides (such ?-helical peptides,...

Abstract Peptides with strong binding affinities for poly(methyl methacrylate) (PMMA) resin were designed by use of materials informatics technology based on molecular dynamics simulation the purpose covering surface adhesive peptides, which expected to result in eco-friendly and biocompatible biomaterials. From results affinity obtained this simulation, it was confirmed that experimental value...

The phenomenon of antimicrobial resistance threatens our ability to treat common infections. clinical pipeline for new antimicrobials is pretty much dry and hence, there a need the development agents with low toxicities help fight resistant microorganisms. This work aimed design peptides using database filtering technology evaluate their bioactivities. physicochemical properties designed were e...

Antibacterial Fabrics In article number 2201061, Eduardo Barbieri, Stefano Menegatti, and colleagues present scalable methods to produce antibacterial fabrics by functionalizing nonwoven fiber mats with antimicrobial peptides polymers. Microgels are photo-crosslinked on nonwovens fibers utilized load release peptides. Selected affording sustained of show activity against bacteria Staphylococcus...