BACKGROUND Asthma is a disease resulting from a complex interaction of multiple genetic and environmental factors. More than 200 asthma candidate genes have been identified in the past decades by using genetic association studies, positional cloning and knockout mouse approaches. AIM This study was to identify differentially expressed genes and provide direction for medicine design related to...

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is primarily transmitted through the eyes, nose, or mouth. Ophthalmic complications, such as conjunctivitis and dacryoadenitis, have been reported in patients with disease 19 (COVID-19). We report case of an early adolescent girl who presented bilateral urticarial rashes, eyelid edema, fever, cough. She was diagnosed dacryoadenitis SA...

patients and materials this was a across-sectional prospective study performed at the pediatric department of rasoul hospital, tehran, iran (2009-2011) on 80 hospitalized children with viral age. all stool samples were collected on viral transport media. human bocavirus (hbov) was detected using the real-time pcr taqman method. molecular detection of human parechovirus type 1 (hpev-1) rna in st...

Acute acalculous cholecystitis (AAC) is an inflammation of the gallbladder, which does not appear to be associated with the presence of gallstones. AAC is estimated to represent more than 50% of cases of acute cholecystitis in the pediatric population. Although this pathology was initially described in critically ill patients, actually most pediatric cases have been observed during several infe...

Introduction B cells play an integral role in the immune response to both dengue fever and COVID-19. Prior scRNAseq analyses of peripheral plasmablasts COVID-19 have revealed a heterogeneous population with distinct cell subsets associated proliferation; prior studies patients likewise shown presence proliferative pre-plasmablasts circulation. These findings may implications for disease severit...

OBJECTIVE To determine the pattern of childhood dermatoses in Eastern province of Saudi Arabia (SA), in the setting of a university-affiliated hospital, and to compare this with other similar surveys conducted in SA. METHODS This is a retrospective study of pediatric patients attending the outpatient dermatology clinic and dermatology emergency room at King Fahad Hospital of the University, A...