Having a preliminary place and paramount significance among Yaşar Kemal’s historical fiction novels, Look, the Euphrates River is Flowing Blood first book of his quartet entitled “An Island Tale” that was published in 1997. Dealing with ordeal uncanny feelings Anatolian people after First World War, Kemal recounts material spiritual destruction caused by phenomenon migration both within beyond ...

Patients with progressive renal insufficiency (PRI) who start renal replacement therapy (RRT) within 4 months of seeing a nephrologist (late referral) have increased morbidity, mortality, and health care costs. We performed an economic evaluation of early versus late referral of patients with PRI to a multidisciplinary clinic. A decision analysis was performed from the perspective of the health...

Using a helicopter-mounted portable spectroradiometer and continuous eddy covariance data we were able to evaluate the photochemical reflectance index (PRI) as an indicator of canopy photosynthetic light-use efficiency (LUE) in four boreal forest species during the Boreal Ecosystem Atmosphere experiment (BOREAS). PRI was calculated from narrow waveband reflectance data and correlated with LUE c...

MicroRNAs (miRNAs) regulate the expression of a large number of protein-coding genes. Their primary transcripts (pri-miRNAs) have to undergo multiple processing steps to reach the functional form. Little is known about how the processing of miRNAs is modulated. Here we show that the RNA-binding protein DiGeorge critical region-8 (DGCR8), which is essential for the first processing step, is a he...

15 Refugia can affect predator-prey dynamics via movements between refuge and non-refuge areas. We examine 16 the influence of a refuge on population dynamics in a large mammal predator-prey system. Wolves (Canis 17 lupus) have recolonized much of their former range in North America, and as a result, ungulate prey have 18 exploited refugia to reduce predation risk with unknown impacts on wolf-p...

The Escherichia coli primosome is a mobile multiprotein DNA replication-priming apparatus that assembles at a specific site (termed a primosome assembly site (PAS] on single-stranded DNA-binding protein-coated single-stranded DNA. The PRI A protein (factor Y, protein n') is a PAS sequence-specific (d)ATPase as well as a DNA helicase and is believed to direct the assembly of the primosome at a P...

Major RNA products of a microRNA (miRNA) gene--the long primary transcript (pri-miRNA), the ∼70-nucleotide (nt) precursor miRNA (pre-miRNA), and the ∼21-nt mature miRNA--all contain the same sequence required for target gene recognition. Thus, it is intrinsically difficult to discern the contribution of individual RNA species or to rule out a function of miRNA precursor species in target repres...

The refuge strategy can delay resistance of insect pests to transgenic maize producing toxins from Bacillus thuringiensis (Bt). This is important for the western corn rootworm, Diabrotica virgifera virgifera LeConte (Coleoptera: Chrysomelidae), because of its history of adaptation to several management practices. A 2-yr study across four locations was conducted to measure the effects of integra...

At the intersection of consumer behaviour and plant competition is the concept of refuge-mediated apparent competition: an indirect interaction whereby plants provide a refuge for a shared consumer, subsequently increasing consumer pressure on another plant species. Here, we use a simple model and empirical examples to develop and illustrate the concept of refuge-mediated apparent competition. ...

BACKGROUND Patients often fail to stop clopidogrel appropriately before non-cardiac surgery. Thromboelastography platelet mapping (TEG-PM) can be used to measure the percentage adenosine 5'-diphosphate platelet receptor inhibition (ADP-PRI) by clopidogrel in these patients. METHODS This prospective case-control study investigated the risk of bleeding in patients who had taken clopidogrel with...