Female genital tuberculosis (FGTB) has a crucial role in many gynaecological complaint and delay diagnosis can cause irreversible damages. The new diagnostic technique GeneXpert system is accurate rapid test make paradigm shift FGTB treatment. aim of the study to estimate efficacy different tests i.e. AFB BACTEC culture, molecular assay (TB-PCR) histopathology comparison detect FGTB. prospectiv...

Acute promyelocytic leukemia (AML M3) is a well-defined subtype of leukemia with specific and peculiar characteristics. Immediate identification of t(15;17) or the PML/RARA gene rearrangement is fundamental for treatment. The objective of the present study was to compare fluorescent in situ hybridization (FISH), reverse transcriptase-polymerase chain reaction (RT-PCR) and karyotyping in 18 samp...

We tested rectal specimens from men who have sex with men for Chlamydia trachomatis by using COBAS PCR (Roche Diagnostics) and ligase chain reaction LCR (Abbott laboratories) and compared three PCR specimen-processing procedures. Chlamydiae were detected by one or more procedures in 22 of 186 specimens. All three PCR tests were positive for 17 specimens, all of which also tested positive by LCR.

Currently, the second- and third-generation enzyme immunoassays (EIA-2 and EIA-3) for hepatitis C virus antibody (anti-HCV) are the most practical screening tests for the diagnosis of HCV infection. The need for and the choice of supplementary or confirmatory tests depend on the clinical setting and the likelihood of a true-positive EIA result. Detection of HCV RNA in serum by polymerase chain ...

In human African trypanosomiasis (HAT), two disease stages are defined: the first, or haemo-lymphatic stage, and the second, or meningo-encephalitic stage. Stage determination forms the basis of therapeutic decision and is of prime importance, as the drug used to cure second-stage patients has considerable side-effects. However, the tests currently used for stage determination have low sensitiv...

BACKGROUND Leptospirosis is a neglected zoonosis affecting mainly tropical and subtropical regions worldwide, particularly South America and the Caribbean. As in many other countries, under-reporting of cases was suspected in the French West Indies because of inadequate access to diagnostic tests for the general population. METHODOLOGY/PRINCIPAL FINDINGS In order to estimate the real incidenc...

IntroductionCoronavirus disease 2019 [COVID-19] has become a pandemic resulting in large number of deaths. The compl icat ions COVID-19 are severe post -transplantation patients on immunosuppression, more mortality. Therefore renal transplantations [KT] were stopped temporarily Sri Lanka during the peak epidemic. And few months later when KT was restarted only who real-time polymerase chain rea...

Two separate studies (study I and study II) were conducted to evaluate the efficacy of ELISA serological test for the detection of IgG antibodies against specific glycolipid antigen (PGLTb1) and ESAT 6 antigen of Mycobacterium tuberculosis, respectively. These results were compared with bacteriological tests [Ziehl Neelson (ZN) staining for acid-fast bacilli and culture on Lowenstein Jensen (LJ...

CMV diseases predominantly occur as an opportunistic infection in patients with severe immunosuppression, such as cancer and renal failure patients, and rarely occur in immunocompetent patients. This study aimed to investigate the prevalence of CMV infection in patients undergoing hemodialysis and to compare the results of different serological tests for CMV infection. Data were collected from ...

Objectives To examine the interactions between SARS-CoV-2 positive players and other during rugby league matches determine within-match transmission risk. Methods Four Super League in which were subsequently found to have participated analysed. Players identified as increased-risk contacts, player proximities analysed by video footage global positioning system (GPS) data. The primary outcome wa...