BACKGROUND Acute ST-elevation myocardial infarction (STEMI) is associated with significant arrhythmia and cardiac arrest. QT prolongation can occur in the setting of ischemia or acute STEMI as a risk factor for arrhythmia. The goal of this study was to investigate corrected QT interval (QTc), QT dispersion (QTd), and T-wave peak to end (TPE) times in this patient population and evaluate the eff...

Introduction: Protein C inhibitor (PCI) was initially found in human plasma as an inhibitor of activated protein C (APC), the main protease of the anticoagulant protein C pathway [1]. PCI has a reactive site (354Arg-355Ser), which is important for inhibition of serine proteases; therefore, PCI is categorized as a member of the serine protease inhibitor (SERPIN) family [2]. Subsequent studies re...

BACKGROUND It is unclear whether facilitated percutaneous coronary intervention (PCI) via a transradial approach therapy is preferable to primary PCI, with improved ventricular synchrony performance (VS), in Chinese patients. METHODS AND RESULTS The 152 patients with their first anterior acute myocardial infarction (AMI) were randomized to a primary PCI group or facilitated PCI group. In the ...

OBJECTIVE Depression is present in 1 of 5 outpatients with coronary artery disease (CAD), and a well-documented risk factor for recurrent cardiac events and mortality. We examined the impact of percutaneous coronary intervention (PCI), on depressive symptoms, in chronic stable angina (CSA) patients. METHODS On prospective and non-randomized trial, consecutive CSA patients (n=171), who had und...

Primary percutaneous coronary intervention (PCI) has been demonstrated to be superior to fibrinolytic therapy in reducing mortality in ST-segment elevation myocardial infarction (STEMI) when it can be performed rapidly. However, many STEMI patients present to hospitals without PCI capability and often cannot undergo PCI within the guideline-recommended timelines; instead, they receive fibrinoly...

OBJECTIVES Our aim was to compare longer-term outcomes for ad hoc percutaneous coronary intervention (PCI) and non-ad hoc PCI. BACKGROUND Ad hoc PCIs, whereby PCI is performed immediately after cardiac catheterization, has become the most common way of performing PCI. However, no studies have compared longer-term outcomes for ad hoc and non-ad hoc PCIs. METHODS A total of 46,565 New York St...

BACKGROUND Primary percutaneous coronary intervention (PCI) is more effective on average than fibrinolytic therapy in the treatment of ST-segment-elevation myocardial infarction. Yet, most US hospitals are not equipped for PCI, and fibrinolytic therapy is still widely used. This study evaluated the comparative effectiveness of ST-segment-elevation myocardial infarction regionalization strategie...

OBJECTIVES To study the causes of and to develop a risk score for failure of transradial approach (TRA) for percutaneous coronary intervention (PCI). BACKGROUND TRA-PCI failure has been reported in 5% to 10% of cases. METHODS TRA-PCI failure was categorized as primary (clinical reasons) or crossover failure. Multivariate analysis was performed to determine independent predictors of TRA-PCI ...

2610 Introduction In 2007, the Society for Cardiovascular Angiography and Interventions (SCAI) published an Expert Consensus Document titled “The Current Status and Future Direction of Percutaneous Coronary Intervention without On-Site Surgical Backup.” This document summarized the available data on the performance of percutaneous coronary intervention (PCI) without on-site surgery in the Unite...

BACKGROUND The success of prehospital triage protocols for patients with ST-elevation myocardial infarction (STEMI) will depend, in part, on how patients are geographically distributed around hospitals that perform percutaneous coronary intervention (PCI). Accordingly, we determined the proportion of the adult population in the United States with timely access to PCI hospitals using driving tim...