The aim of this study was to determine the levels of six polychlorinated biphenyls (referred to as PCB-28, PCB-52, PCB-101, PCB-138, PCB-153 and PCB-180, according to the IUPAC) in freshwater fish from the Zagreb area. A total of 216 samples was collected from five sites: from the Sava River upstream of Zagreb, in Zagreb, and downstream of Zagreb, from Lake Jarun, and from five fishponds from t...

Although banned from production in the United States and other developed countries in the late 1970s, polychlorinated biphenyls (PCBs) remain widespread environmental contaminants found in measurable amounts in the general population. These compounds have been linked to longer time to pregnancy and increased preg nancy loss in both epidemiologic and experimental research. A new study pinpoints ...

Although banned from production in the United States and other developed countries in the late 1970s, polychlorinated biphenyls (PCBs) remain widespread environmental contaminants found in measurable amounts in the general population. These compounds have been linked to longer time to pregnancy and increased preg nancy loss in both epidemiologic and experimental research. A new study pinpoints ...

BACKGROUND Recent findings suggest that exposure to organochlorine (OC) compounds, chlordanes and p,p'-dichlorodiphenyldichloroethylene (p,p'-DDE) in particular, may increase the risk of developing testicular germ cell tumors (TGCTs). OBJECTIVE To further investigate this question, we conducted a nested case-control study of TGCTs within the Norwegian Janus Serum Bank cohort. METHODS The st...

Previous studies have described high levels of polychlorobiphenyls (PCB), polybrominated diphenylether (PBDE), toxaphene, p,p'-dichlorodiphenyltrichloroethane (DDT), and p,p'-dichlorodiphenyldichloroethylene (DDE) in the blubber of the harbour porpoise from the North Sea raising the question of a potential endocrine disruption in this species. In the present study, the thyroids of 57 harbour po...

Previous studies showed exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD) enhances the development of endometriotic lesions. In this study we examined the effects of other polyhalogenated aromatic hydrocarbons on endometriotic proliferation. B6C3F1 female mice were treated via oral gavage a total of five times, with 3 weeks between each dosing, with 0, 1, 3, or 10 micrograms 2,3,7,...

We examined the influence of widely varied consumption of fatty fish from the Baltic Sea and of age on plasma concentrations of polychlorinated biphenyls (PCBs), polychlorobiphenylols (OH-PCBs), 2, 2-bis(4-chlorophenyl)-1,1,1-trichloroethane (4,4'-DDT), 2, 2-bis(4-chlorophenyl)-1,1-dichloroethane (4,4'-DDE), 2,2',4, 4'-tetrabromodiphenyl ether (BDE-47), hexachlorobenzene (HCB), and pentachlorop...

The organochlorines, dichloro-diphenyl-trichloroethane and polychlorinated biphenyl (PCB) are pervasive environmental contaminants. Results from previous studies have been conflicting regarding the relationship between the internal dose of these organochlorine residues and breast cancer risk. To determine whether these compounds are present in breast cyst fluids and whether cyst fluid and plasm...

To verify a theoretical mass balance and multiple compartment partitioning model developed to predict freely dissolved concentrations (FDCs) of hydrophobic organic chemicals (HOCs) using negligible depletion-solid phase microextraction (nd-SPME), a series of sediment slurry experiments were performed using disposable poly(dimethyl)siloxane (PDMS) coated-SPME fibers and (14)C-radiolabeled HOC an...

Although the brain continues developing in the postnatal period, epidemiological studies on the effects of postnatal exposure to neurotoxic POPs through breast-feeding remain mostly inconclusive. Failure to detect associations between postnatal exposure and health outcomes may stem from the limitations of commonly employed approaches to assess lactational exposure. The aim of the present study ...