discussion while this novel type of drug delivery is known as a suitable substitute for oral and parenteral administration, it was well accepted and extensively mentioned in persian medical and pharmaceutical manuscripts and other traditional systems of medicine as well. accordingly, medieval pharmaceutical standpoints on nasal dosage forms could still be an interesting subject of study. theref...

OBJECTIVES To evaluate the knowledge, attitude and practice of consumers in India about disposal of unused medicines. MATERIALS AND METHODS A questionnaire comprising 11 questions evaluating the Knowledge (2), Attitude (3) and Practice (6) of unused medicines was prepared and pre validated before administering to 200 consumers of medicines attending the outpatient department of Civil Hospital...

Aim Extending and generalizing the computational concept of analog series-based (ASB) scaffolds. Materials & methods Methodological modifications were introduced to further increase the coverage of analog series (ASs) and compounds by ASB scaffolds. From bioactive compounds, ASs were systematically extracted and second-generation ASB scaffolds isolated. Results More than 20,000 second-gener...

AIM Computational design of and systematic search for a new type of molecular scaffolds termed analog series-based scaffolds. MATERIALS & METHODS From currently available bioactive compounds, analog series were systematically extracted, key compounds identified and new scaffolds isolated from them. RESULTS Using our computational approach, more than 12,000 scaffolds were extracted from bioa...

OBJECTIVES Developing countries face considerable problems in both accessing and properly utilizing essential medicines. One challenge to achieving these goals in resource-poor settings is a limited knowledge base as to what works to improve the selection, access and use of essential medicines including; ways to ensure affordable prices, increase sustainable financing, and strengthen reliable s...

This document presents a readability test designed to optimise the readability of package leaflets for medicinal products. Patients often find leaflets incomprehensible, which in part explains the high percentage of medications disposed of before being taken. So patient information must be formulated that an averagely educated user can understand its content and follow its instructions. The pap...

Hiroshi Sakagami1, Tatsuya Kushida2, Toru Makino3, Tsutomu Hatano4, Yoshiaki Shirataki5, Tomohiko Matsuta1, Yukiko Matsuo6 and Yoshihiro Mimaki6 1Meikai University School of Dentistry, Saitama, 2Non-Profit Organization Bio-Knowledge Bank, Tokyo, 3HumaLabo Co., Ltd., Tokyo, 4Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, 5Faculty of Pharmaceutica...

background: lidocaine is a local anesthetic and antiarrhythmic agent. there are reports on accidental and intentional cases of poisoning following injection of lidocaine while rare are the fatal cases realized after oral ingestion of lidocaine. suicidal poisoning with lidocaine pharmaceutical formulations is rare since no pharmaceutical dosage forms for oral use are available except gels and sp...

the pharmaceutical knowledge and the medical science are very old in iran. during sassanid era, people who studied medicine or pharmacy at gondi-shapour university, had permission to treat sick people. after interruption in the progress of medicine and pharmacy, during the islamic civilization, these sciences were spread and became under control of the government. this research has presented th...