Purpose To examine posterior staphylomas by widefield optical coherence tomography (WF-OCT) and three-dimensional magnetic resonance imaging (3D-MRI). Methods Highly myopic patients (myopic refractive error >8.0 diopters or axial length >26.5 mm) who had previously undergone orbital 3D-MRI were examined by WF-OCT. Results The study included 100 eyes of 57 patients with a mean age of 67.9 ± ...

BACKGROUND To determine the prevalence and associated factors for myopia and high myopia among older population in a rural community in Eastern China. METHODS A community-based, cross-sectional survey was conducted in the Weitang town located in Suzhou, an urban metropolis in East China. A total of 5613 Chinese residents aged 60 years and older were invited to complete a questionnaire and par...

PURPOSE To determine the risk factors of incident myopia in a school-based cohort study in Singaporean children. METHODS A 3-year prospective cohort study was conducted in Singaporean school children aged 7 to 9 years in three schools at entry. Chinese children without myopia at baseline (n = 994) were included in the analysis. The main outcome was incident myopia, defined as spherical equiva...

aim : the aim of this study was to comprehensively analyze histopathologic parameters of whipple pancreaticoduodenectomy specimens at taleghani general hospital pathology department. background : the whipple procedure is performed for variety of tumors involving the head of the pancreas, ampulla of vater, common bile duct, or duodenum. patients and methods : records of all cases of whipple panc...

Myopia—time preference—has been shown to be commonplace and is believed to lead to a series of negative outcomes, such as overconsumption and addiction. Yet, little is known about the determinants of myopia. Using a random-assignment experiment, we investigate whether happiness decreases myopia. Subjects are randomly assigned to receive a happyor neutral-affect inducement. Immediately following...

High myopia is one of the leading causes of blindness worldwide. However, the exact etiology of high myopia remains unraveled despite numerous attempts of elucidation. Previous genome-wide association study (GWAS) has revealed that four single nucleotide polymorphisms (SNPs), including rs2969180, rs1652333, rs9307551, and rs7837791, were associated with high myopia in Caucasians. The present st...

INTRODUCTION The prevalence of myopia amongst the Chinese has escalated in recent decades. While this refractive error was previously a little more than an inconvenience and a source of unwanted expense to the affected individuals, it is now sufficiently prevalent to warrant national concern. Myopia is also a major cause of low vision. This review aims to provide information on the prevalence o...

PURPOSE The mechanism of axial elongation in the myopic eyeball remains to be elucidated. It is known that the expression profile for some proteins in the aqueous humor (AH) changes in some diseases. Accordingly, determinations of these AH proteins may serve to understand their potential role in this pathogenesis. To identify the possible mechanism in myopia development, a proteomic analysis of...

PURPOSE Evidence from human myopia genetic mapping studies (MYP3 locus), modulated animal models, and observations of glycemic control in humans suggests that insulin-like growth factor (IGF)-1 plays a role in the control of eye growth. This study was conducted to determine whether IGF-1 polymorphisms are associated with myopia in a large, international dataset of Caucasian high-grade myopia pe...