Mucoadhesive buccal patch releasing drug in the oral cavity at a predetermined rate may present distinct advantages over traditional dosage forms, such as tablets, gels and solutions. A buccal patch for systemic administration of acyclovir in the oral cavity was developed using polymers hydroxy propyl methyl cellulose (K4M), hydroxy propyl methyl cellulose (K15M), sodium carboxy methyl cellulos...

We formulate a two-patch mathematical model for Ebola Virus Disease dynamics in order to evaluate the effectiveness of cordons sanitaires, mandatory movement restrictions between communities while exploring their role on disease dynamics and final epidemic size. Simulations show that severe restrictions in movement between high and low risk areas of closely linked communities may have a deleter...

a study was performed in hybrid up flow anaerobic sludge blanket (huasb) and anaerobic filter (af) reactors to compare the start-up time and optimum hrt required for the treatment of poultry slaughterhouse wastewater under similar loading conditions. initially, the reactors were started at an olr of 0.77 kg cod/m3.d and hrt of 36 h. loading rates were increased by reducing hrt 24, 16, 12, 10 an...

1. Animals usually require information about the current state of their habitat to optimize their behaviour. For this, they can use a learning process through which their estimate is continually updated according to the cues they perceive. Identifying these cues is a long-standing but still inveterate challenge for ecologists. 2. The use of plant cues by aphid parasitoids for the assessment of ...

A pharmacokinetic and bioavailability study of sulfadiazine combined with trimethoprim (sulfadiazine/trimethoprim) was carried out in fifteen healthy young ostriches after intravenous (i.v.), intramuscular (i.m.) and oral administration at a total dose of 30 mg/kg body weight (bw) (25 and 5 mg/kg bw of sulfadiazine and trimethoprim, respectively). The study followed a single dose, three periods...