The control and treatment of infectious diseases is increasingly complicated by the development of antibiotic-resistant organisms, the emergence and rapid dissemination of new pathogens, and the growing incidence of opportunistic infections. Identification and commercialization of new anti-microbial agents has always been a time-consuming and expensive process, and development of new strategies...

A Plasmodium knowlesi infection in rhesus monkeys is almost invariably fatal. This infection, however, may be made chronic by the early administration of antimalarial drugs. The animals then will harbor a chronic infection for an indefinite period. The serum taken from monkeys with chronic infection and injected into those suffering from an acute attack was found to have a definite depressing e...

This study examined the acute immunological effects of two laboratory stressors, expected to evoke distinct patterns of cardiac autonomic activity; namely an "active coping" time-paced memory test, and a "passive coping" stressful video showing surgical operations. We measured salivary S-IgA, IgA-subclasses (IgA1, IgA2), and secretory component (SC). SC is responsible for the transport of S-IgA...

OBJECTIVE To evaluate the effect of orally administered cisapride, bethanechol, and erythromycin on the absorption of colostral IgG in dairy calves. ANIMALS Twenty-four healthy neonatal Holstein-Friesian calves. PROCEDURES Calves were randomly assigned to one of the following treatments: 0.9% NaCl solution (2 mL, p.o.; negative control); erythromycin lactobionate (20 mg/kg BW, p.o.; anticip...