The author describes the case of a 2-year-old boy presenting with aplastic anaemia due to documented parvovirus infection bone marrow without specific seroconversion.

Transplant recipients are known to be susceptible to primary viral infections or to reactivation of a persistent virus. Most of the clinically relevant infections are caused by the herpes-viridae group (CMV, EBV, VZV, HSV I and II). Human parvovirus B19 was first discovered 1975 in human packed blood [1] and subsequently shown to cause fifth disease or erythema infectiosum in children [2]. The ...

BACKGROUND Infection with parvovirus B19 may cause fetal losses including spontaneous abortion, intrauterine fetal death and non-immune hydrops fetalis. The aim of this study is to determine the frequency of parvovirus B19 in formalin fixed placental tissues in lost fetuses using real-time PCR method. METHODS In this cross-sectional study, 100 formalin fixed placental tissues with unknown cau...

Parvovirus B19 infection is usually self-limiting in immunocompetent individuals. Twenty-five percent of infected individuals are
 completely asymptomatic during infection, with 50% them presenting flu-like symptoms and the remaining patients presenting
 erythema infectiosum, arthralgia, or arthritis. More rarely, transient aplastic crisis seen chronic haemolytic
 disorders. Chro...

BACKGROUND The incidence of acute symptomatic (at the time of documented brain insult) seizures and single unprovoked seizures are 29-39 and 23-61 per 100 000 per year, respectively. After stabilization of the patient, finding the etiology of the seizure is of paramount importance. A careful history and physical examination may allow a diagnosis without need for further evaluation. METHODS In...

OBJECTIVE To augment the understanding of parvovirus B19 infection in pregnancy with respect to maternal characteristics and their corresponding fetal outcomes. STUDY DESIGN Retrospective case-series of all women referred to Magee-Women_s Hospital with serologically-documented parvovirus B19 infection during pregnancy from 1998-2001. RESULTS All 25 cases that are available for analysis occu...

BACKGROUND Because parvovirus B19 infection in pregnancy has been associated with infant morbidity and mortality in case reports and after intrauterine transfusion, we tested the population-based association using serum and hospital data of high quality. METHODS We established a cohort of 113 228 children born to women tested for parvovirus B19 infection during pregnancy in a major diagnostic...

Human parvovirus 4 (PARV4) has been detected in blood and diverse tissues samples from HIV/AIDS patients who are injecting drug users. Although B19 virus, the best characterized human parvovirus, has been shown to co-infect patients with hepatitis B or hepatitis C virus (HBV, HCV) infection, the association of PARV4 with HBV or HCV infections is still unknown.The aim of this study was to charac...

BACKGROUND AND OBJECTIVES The clinical features of parvovirus B19 infection in adult patients have not been well described. The aim of this prospective study was to clarify the clinical features of adult patients with parvovirus B19 infection in primary care settings. METHODS The study subjects were adults over age 18 years who had visited one primary care clinic over a period of one year. Th...

Human parvovirus 4 (Parv4) is a relatively new virus. Association of this virus with any human disease is yet to be established. We detected human parvovirus 4 in the cerebrospinal fluid (CSF) of two patients presenting with acute encephalitis syndrome in northern India. This is the first report of the Parv4 genome sequence from northern India.