The Focus article "Double Exposure" [EHP 107:A196-A201 (1999)] mistakenly reported that a meta-analysis of epidemiology studies examining the relationship between exposure to environmental tobacco smoke (ETS) and human cancer was prepared for the review of ETS in consideration for listing in the National Toxicology Program (NTP) Report on Carcinogens. We would like to point out that the results...

Title: There is no relationship between Paraoxonase serum level activity in women with endometriosis and the stage of the disease: an observational study

The importance of high-density lipoprotein (HDL) particle components to reproduction is increasingly recognized, including the constituent paraoxonase 1 (PON1). However, the reliability characteristics of PON1 enzymes in ovarian follicular fluid (FF) as biomarkers for clinical and epidemiologic studies have not been described. Therefore, we characterized PON1 enzymes in FF and serum and assesse...

Introduction and Aim: CKD (Chronic Kidney Disease) is a problem in health care spread all over the world with adverse consequences. associated premature atherosclerosis increased morbidity mortality due to cardiovascular complications. Hypertriglyceridemia commonly seen lipid abnormality patients. PON-1 (Paraoxanase-1) glycoprotein synthesized liver released into blood, where it links HDL. This...

Oxidative stress is involved in the pathogenesis of asthma. Paraoxonase 1 (PON1) and arylesterase are esterase enzymes displaying antioxidant characteristics. PON1 activity varies widely among individuals and ethnic groups, partly related to polymorphisms. The aim of this study was to determine the activities of PON1 and arylesterase including the phenotype distribution of PON1 in asthmatic pat...

diabetes is one of the most common metabolic diseases in the world. vitamin e reduces protein glycation and improves insulin sensitivity, while cumin is effective in remission of diabetes. therefore this study was designed to evaluate the effects of vitamin e and cumin essential oil, on the blood level of leptin,glycosylated hemoglobin (hba1c) and also on lipid profile in diabetic patients.in t...

background: dyslipidemia is considered an independent risk factor for coronary heart disease (chd). in the present study, we examined lipid profiles and paraoxonase 1 (pon1) activity and atherogenic indexes status and the relationship of pon1 activity by high-density lipoprotein (hdl) and atherogenic indexes in chd patients and healthy people. methods: the aim of the study was to compare pon1, ...