Sulfonic acid functionalized SBA-15 as a nanoporous acid catalyst was used in the synthesis of 2-Aryl benzoxazoles 4 by the condensation of 2-aminophenol 1 and benzoyl chlorides 2 under microwave irradiation in solvent free reaction conditions. The advantages of this methodology are good product yields (60-98%), being environmentally benign, short reaction times and easy work up.

It has been demonstrated by many workers (l-5) that phenols may be conjugated with glucuronic acid or inorganic sulfate in vitro by liver slices and by cell-free preparations. By using a system developed in this laboratory, together with a modification of the analytical procedure described by Levvy and Storey (3), the synthesis of the conjugated sulfate, and possibly of the glucuronide, has bee...

Ligas Fe-Co foram depositadas e dissolvidas em solução contendo íons metálicos e em solução de NH 4 Cl. Resultados voltamétricos sugerem interação entre os componentes da liga, originando uma solução sólida. Perfis de ALSV apresentam diferenciação para o processo de dissolução dos metais individuais e das ligas, com comportamento semelhante ao observado para cobalto e/ou ferro, com deslocamento...

A new variant of Local Linearization (LL) method is proposed for the numerical (strong) solution of differential equations driven by (additive) alpha-stable Lévy motions. This is studied through simulations making emphasis in comparison with the Euler method from the viewpoint of numerical stability. In particular, a number of examples of stiff equations are shown in which the Euler method has ...

An arylamine N-acetyltransferase (NAT) responsible for the N acetylation of exogenous 3-amino-4-hydroxybenzoic acid in Streptomyces griseus was identified and characterized. This enzyme was distinct from other eukaryotic and bacterial NATs in that it acetylated various 2-aminophenol derivatives more effectively than it acetylated 5-aminosalicylic acid, and thus it may be involved in the metabol...

A new phenylpropanoid glycoside (1), and two new coumarin glycosides (2, 3), together with two known compounds (4, 5), have been isolated from the stems of Hydrangea paniculata Sieb. Their structures have been determined by spectroscopic and chemical methods. Furthermore, compound 1 (50 μM) exhibited significant hepatoprotective activity against N-acetyl-p-aminophenol (APAP)-induced HepG2 cell ...

A nitridoosmium(VI) complex [Os(VI)(N)(sap)(OH(2))Cl] (H(2)sap = N-salicylidene-2-aminophenol) displays prominent in vitro and in vivo anti-cancer properties, induces S- and G2/M-phase arrest and forms a stable adduct with dianionic 5'-guanosine monophosphate.