In this paper, we propose an original method to include spatial panning information when converting monophonic recordings to stereophonic ones. Sound sources are first identified using perceptually motivated clustering of spectral components. Correlations between these individual sources are then identified to build a middle level representation of the analysed sound. This allows the user to de...

In cabbage, glucosinolates such as sinigrin are hydrolyzed by plant myrosinase to allyl isothiocyanate (AITC), allyl cyanide, and, in the presence of an epithiospecifier protein, 1-cyano-2,3-epithiopropane (CEP). Isothiocyanates have been implicated in the cancer-protective effects of Brassica vegetables. The effect of processing on the hydrolysis of glucosinolates was investigated in cabbage. ...

The delivery of educational content via a web browser over the Internet anytime and anywhere is emerging as a new education channel. Today's rapidly changing technological environment demands that faculty maintain technological currency. Computer based and other tutorials have demonstrated success in helping faculty maintain technological competence and currency in the academic arena in the pas...

Biopanning has been used extensively in conjunction with purified components, but there are also examples in which mixtures of targets have been investigated. This study introduces a methodological innovation, termed iterative panning and blocking (IPAB), to extend the range of specific interactions that can be probed in mixtures. Here this procedure is used to probe a mixture of high molecular...

A large naı̈ve human single-chain (sc) Fv phage library was used to search for tumor-associated antigens by panning with a lung adenocarcinoma cell line, 1264, and counter-selecting with a nontumor bronchial epithelial cell line, BEAS-2B. After three rounds of subtractive panning, 239 of 673 clones analyzed bound selectively to 1264 tumor cells in a phage ELISA. Diversity analysis of these tumor...

Background for slow steaming A combination of factors have led to the past two years becoming hugely challenging for certain sectors of the global merchant shipping industry. Th ese factors include: Th e downturn in the global economy, resulting in reduced transportation capacity demand Th e substantial global order book for new tonnage, a legacy from the boom years, resulting in record-high de...

Long insertions into a loop of a folded host protein are expected to have destabilizing effects because of the entropic cost associated with loop closure unless the inserted sequence adopts a folded structure with amino- and carboxy-termini in close proximity. A loop entropy reduction screen based on this concept was used in an attempt to retrieve folded sequences from random sequence libraries...

Ecotin, a dimeric serine protease inhibitor from Escherichia coli, is a novel platform for inhibitor design. An approach using the three-dimensional structure of the ecotin-trypsin complex to guide combinatiorial design efforts was taken to create potent bidentate ecotin inhibitors for trypsin and human urokinase-type plasminogen activator (uPA). The ecotin surface loop that was redesigned is c...

This study compares the stage metaphor and the channel strip metaphor in terms of performance. Traditionally, music mixing consoles employ a channels strip control metaphor for adjusting parameters such as volume and panning of each track. An alternative control metaphor, the so-called stage metaphor lets the user adjust volume and panning by positioning tracks relative to a virtual listening p...