نتایج جستجو برای: pain modulation

تعداد نتایج: 392168  

Journal: :Canadian Journal of Gastroenterology 1999

Journal: :Journal of Neuroscience 2009

Journal: :International journal of clinical and experimental medicine 2015
Gong-Ming Wang Xiao-Yan Wang Guang-Jie Liu Kun Cheng Hua Wang Shou-Gang Guo

OBJECTIVE Peripheral nerve injury elicits an aversive state of spontaneous neuropathic pain, and up to now, the modulation of this concomitant aversive state remains a major therapeutic challenge. NMDA receptor subunits NR2B in the rACC are critically involved in the processing of this aversive state and then a strategy targeted at the NR2B subunit might be promising for modulation of the avers...

Journal: :Physical therapy 2021

Abstract Objective Given the complex and unclear etiology of neck pain, it is important to understand differences in central sensitization as well psychosocial factors individuals with chronic pain healthy controls. The purpose this study was benchmark sensitization, factors, range motion between people nonspecific controls analyze correlation intensity, disability, pain. Methods Thirty 30 were...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2009
Frank Seifert Kathrin Bschorer Roberto De Col Jörg Filitz Elena Peltz Wolfgang Koppert Christian Maihöfner

Sodium channel blockers are known for reducing pain and hyperalgesia. In the present study we investigated changes in cerebral processing of secondary mechanical hyperalgesia induced by pharmacological modulation with systemic lidocaine. An experimental electrical pain model was used in combination with functional magnetic resonance imaging. After induction of pin-prick hyperalgesia lidocaine o...

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