نتایج جستجو برای: p15ink4b gene

تعداد نتایج: 1141459  

Journal: :Cancer research 1995
R Yang A F Gombart M Serrano H P Koeffler

Several point mutations of p16INK4a were studied by site-specific mutagenesis and functional analysis to assess the effects of these mutations on the function of the protein. These mutations were reported in several malignancies. Three deletional mutants of p16INK4a were also analyzed to reveal the relationship between p16INK4a and p15INK4b and to test the importance of the ankyrin repeats obse...

2016
Jun-jun Qiu Yan Wang Ying-lei Liu Ying Zhang Jing-xin Ding Ke-qin Hua

Antisense non-coding RNA in the INK4 locus (ANRIL) has been implicated in a variety of cancers. In the present study, we evaluated ANRIL expression in epithelial ovarian cancer (EOC) and defined its clinical implications and biological functions. ANRIL was overexpressed in EOC tissues relative to normal controls. Overexpression correlated with advanced International Federation of Gynecologists ...

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