Bile duct ligation causes a five- to sevenfold increase in the activity of rat liver alkaline phosphatase within 12 hours after ligation and a similar rise in the activity of alkaline phosphatase in serum. The increased serum activity is due entirely to the appearance of a new isoenzyme that has the properties of rat liver alkaline phosphatase. The increase in both serum and liver alkaline phos...

The serum Zinc, Alkaline phosphatase activity and Albumin levels of 50 protein energy malnourished children (6 months – 5 years) were compared with those of 50 normal chil-dren. The levels of zinc was found to be significantly low in malnourished groups and tended to vary with the degree of malnutrition as compared to the control group (p<0.001). These levels were lower in children who had skin...

Tuberculous Pleural effusion is one of the most frequent causes of exudates in large series of pleural effusions in immunocompetent patients. The Aim of this study is to estimate enzyme Alkaline Phosphatase levels in serum and pleural fluids of HIV seronegative exudative Tuberculous Pleural fluids and their possible role in the diagnosis of tubercular pleural effusion. Serum and Pleural fluid s...

Human milk is the main source of nutrients for a child during the first months of life. Alkaline phosphatase (EC 3.1.3.1) is a very important enzyme in clinical chemistry because of its activity in various tissues and biological fluids, being an indicator of physiological or diseased states. Milk contains several phosphatases, the principal ones being alkaline and acid phosphomonoesterases whic...

Jejunal biopsy specimens from patients with gluten-sensitive enteropathy (GSE) (obtained during gluten challenge) as well as from normal individuals and patients with other gastrointestinal abnormalities were cultured in vitro for 48 h in the presence or absence of a peptic-tryptic digest (P-T digest) of gliadin. In the absence of gliadin the alkaline phosphatase activity in the biopsy specimen...

Phosphorylation of rabbit skeletal muscle glycogen synthase by cyclic AMP-independent synthase kinase 1 results in the incorporation of 4 mol of PO4/subunit. Incubation of the phosphorylated synthase with rabbit muscle phosphoprotein phosphatase brings about the hydrolysis of phosphates from all four major tryptic peptides and an increase in the synthase activity ratio from 0.01 to 0.85. Incuba...

Some biochemical, haematological and histological responses were studied in rats undergoing a long term feeding with a Telfairia occidentalis-supplemented diet. Biochemical and hematological parameters investigated included serum protein, total cholesterol, lipid peroxidation, haemoglobin, white blood cells, Aspartate aminotransferase, Alanine aminotransferase, Alkaline phosphatase, Glutathione...