BACKGROUND Fewer than 20% of patients with bone cancer who are treated with surgery alone are cured. Even with the best current treatment, surgery combined with chemotherapy, only 60%-80% of patients with nonmetastatic bone cancer and 10% of patients with metastatic bone cancer are cured. Thus far, the reason for treatment failure in the nonresponding subset has not been identified. It has been...

BACKGROUND Incidence of complications and reoperations between pedicle screw (PS) and hybrid instrumentations (HI) are still controversial in adolescent idiopathic scoliosis (AIS) patients. A systematic review and meta-analysis were performed to compare overall complications, reoperations, and radiographic outcomes between the 2 constructs. METHODS Strictly followed the PRISMA 2009 guidelines...

BACKGROUND An increasing number of mindfulness-based stress reduction (MBSR) studies are being conducted with nonclinical populations, but very little is known about their effectiveness. OBJECTIVE To evaluate the efficacy, mechanisms of actions, and moderators of MBSR for nonclinical populations. DATA SOURCES A systematic review of studies published in English journals in Medline, CINAHL or...

BACKGROUND Aim of this study was to evaluate the effectiveness of various surgical interventions for the management of cervical spondylosis due to the ossification of posterior longitudinal ligament (OPLL). METHODS After a comprehensive literature search in electronic databases, studies were selected by following pre-determined eligibility criteria. Random effects meta-analyses were performed...

BACKGROUND Recent scientific reports have mainly focused on the comparison between coronary artery bypass surgery (CABG) and percutaneous coronary intervention. However, the impact of type 2 diabetes mellitus (T2DM) on mortality in patients who were treated by CABG was often ignored. Therefore, we aimed to compare the long-term mortality following CABG in patients with and without T2DM. METHO...

PURPOSE To investigate the association of soccer heading with subclinical evidence of traumatic brain injury. MATERIALS AND METHODS With institutional review board approval and compliance with HIPAA guidelines, 37 amateur soccer players (mean age, 30.9 years; 78% [29] men, 22% [eight] women) gave written informed consent and completed a questionnaire to quantify heading in the prior 12 months...

Isozyme characters, exclusive of allozymes (alleles), are potentially useful in phylogenetic investigations. Such data have been derived from the multilocus L-lactate dehydrogenase (LDH) enzyme system. Among non-avian reptiles, the classes of potential characters include (1) and number of loci encoding LDH, (2) heterotramer patterns, (3) tissue-specific patterns of gene expression, (4) tissue-s...