Açai (Euterpe oleracea Mart.) has recently emerged as a promising source of natural antioxidants. Because increased oxidative stress and impaired antioxidant defense mechanisms are important factors in the development of diabetic complications and many health claims have been reported for açai, the present study was undertaken to evaluate the possible protective effects of açai on the productio...

Chronic hypoxia is associated with muscle wasting and decreased oxidative capacity. By contrast, training under hypoxia may enhance hypertrophy and increase oxidative capacity as well as oxygen transport to the mitochondria, by increasing myoglobin (Mb) expression. The latter may be a feasible strategy to prevent atrophy under hypoxia and enhance an eventual hypertrophic response to anabolic st...

BACKGROUND Oxygen supplementation through Hudson type face mask is frequently used in perioperative settings. Hudson mask is a variable rate performance device with the risk of rebreathing. Studies using capnography to find out an actual fraction of rebreathing in spontaneously breathing patients are not available. AIMS In this study, we analyzed the effects of different flow rates through Hu...

Fetal life elapses in a relatively low oxygen environment. Immediately after birth with the initiation of breathing, the lung expands and oxygen availability to tissue rises by twofold, generating a physiologic oxidative stress. However, both lung anatomy and function and the antioxidant defense system do not mature until late in gestation, and therefore, very preterm infants often need respira...

Though the equation appears complex, it simply means that the oxygen tension in the alveoli is predominantly determined by the concentration of inspired oxygen, the barometric pressure and the carbon dioxide tension in the alveoli. Because carbon dioxide is very freely diffusible across the alveolar membrane, often arterial and alveolar carbon dioxide tension will be equal. That is why PaCO2 wh...

Selenium is a key component of many important enzyme systems, including the glutathione peroxidase (GPX) family of enzymes. Glutathione peroxidases are primarily involved in repairing cell membranes damaged by lipid peroxidation caused by reactive oxygen species. The glutathione peroxidases may also have an anti-inflammatory role. Sepsis is known to cause a significant degree of oxidative stres...

Background Resveratrolis a natural polyphenol found in peanuts and grapes. Resveratrolpossesses antioxidative properties which have shown to reduce the oxidative damage from reactive oxygen species (ROS). Resveratrol also has the ability to attenuate inflammation via inhibiting TNF-a, IL-1b, IL-6, and blocking NF-kB activation. Resveratrol supplementation may have the potential to mitigate the ...

INTRODUCTION Post-stroke hypoxia is common, and may adversely affect outcome. We have recently shown that oxygen supplementation may improve early neurological recovery. Here, we report the six-month outcomes of this pilot study. METHODS Patients with a clinical diagnosis of acute stroke were randomized within 24 h of admission to oxygen supplementation at 2 or 3 L/min for 72 h or to control ...

STUDY OBJECTIVES Patients with COPD have an increased sympathetic modulation and reduced baroreflex sensitivity (BRS). Therefore, we studied the effects of breathing 31% supplemental oxygen (SuppO(2)) on autonomic modulation in a group of COPD patients. DESIGN We measured autonomic modulation before and during the administration of SuppO(2) on 51 patients with COPD using time-frequency analys...