AIM To evaluate the rates of retinopathy without diabetes and diabetic retinopathy (DR), associated with some markers of oxidative stress, antioxidants and cardiometabolic risk factors. METHODS We determined the prevalence of DR in 150 type 2 diabetes mellitus (T2DM) patients, that of retinopathy in 50 non diabetics, the levels of body mass index (BMI), waist circumference (WC), blood pressur...

Experimental evidence indicates a significant role of oxidative stress in the pathogenesis of idiopathic Parkinson’s disease (PD). However, some studies report no decrease in common antioxidants in blood plasma as a marker of oxidative stress (1). The aim of this study was to estimate plasmalogen levels in blood plasma samples of patients with PD, a group of 1-alkenyl-2-acyl-sn-glycero-3-phosph...

Antioxidants are known to play an important role in quenching reactive oxygen species (ROS), thus ameliorating oxidative stress. Since increased metabolism associated with exercise can increase oxidative stress, dietary antioxidants may be a limiting factor in determining aspects of physical performance. Here we tested whether oxidative stress associated with flight exercise of captive adult bu...

Acute kidney injury (AKI) is the common clinical syndrome which is associated with increased morbidity and mortality. The severity extends from less to more advanced spectrums which link to biological, physical and chemical agents. Oxidative stress (OS)-related AKI has demonstrated the increasing of reactive oxygen species (ROS) and reactive nitrogen species (RNS) and the decreasing of endogeno...

background: it has been reported that ischemia-reperfusion is associated with augmentation of oxidative stress and its specific and sensitive markers. oxidative stress may cause atrial fibrillation (af) which is a common consequence after cardiac surgery. dietary supplementation with antioxidants might lower the incidence of af following coronary artery bypass graft (cabg) surgery. materials an...

BACKGROUND Sutherlandia frutescens (L.) R.Br. (SF) is a South African plant that is widely used to treat stress, infections, cancer, and chronic diseases, many of which involve oxidative stress. The aim of the study was to quantitatively assess the antioxidant potential of SF extracts in cell-free system as well as in cell lines. METHODS Dried SF vegetative parts were extracted using six diff...

It has been estimated that about 20% of men and 25% of women between the ages of 65 and 74 have some degrees of chronic kidney. This complication is attributed to oxidative stress. Oxidative stress is an important factor contributing to kidney damage by increasing production of oxidants, particularly insufficiency of endogenous antioxidant defense system. Medicinal plants antioxidants are able ...

Åsgård, R. 2014. Effects of Antioxidants and Pro-oxidants on Oxidative Stress and DNA Damage using the Comet Assay. Studies on Blood Cells from Type 2 Diabetes Subjects and Mouse Lymphoma Cells. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Pharmacy 185. 78 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-8877-2. Diet and oral supplements comprise two ...