grape seed proanthocyanidin (gsp) bears a very powerful antioxidant effects. studies demonstrated that proanthocyanidins protect against free radicals mediated cardiovascular and renal disorders. the present study was designed to assess the effect of gsp on the heart of diabetic rats. forty rats were divided into four groups of 10 animals each: group i: control, group ii: control group were giv...

camel milk has an importance in the treatment of diabetes. it has been shown that the patients who drink camel milk daily, their need to insulin decrease. therefore, this study aimed to investigate the effect of camel milk in comparison with insulin treatment in experimentally-induced diabetes. this study was carried out on forty male new zealand rabbits, divided into four groups with ten rabbi...

objective: it has been shown that deferasirox can reduce blood and tissues lead content in animal models. in this study the effect of deferasirox alone or combined with glycine as an antioxidant was evaluated in chronic cadmium toxicosis in rat. methods: male wistar albino rats were exposed to 200 ppm cadmium in the drinking water for 3 weeks and treated thereafter with deferasirox (140 mg/kg),...

conclusions in the literature, it was observed that short-term msg exposure does not cause significant histological changes in the kidneys, liver, or brain cortex. these findings should be re-evaluated in additional long-term studies. background monosodium glutamate (msg) is a widely-used flavor enhancer and stabilizer in ready-made or packaged foods. the excessive use of msg has been shown to ...

aim: we conducted this study to investigate the role of ramadan fasting on oxidative stress. materials and method: 23 people (16 male, 7 female) aged between 25 and 65 years were recruited in this study. 10cc venous blood samples were taken after 8- to 10- hours fasting on 2 different times: a week before ramadan and at the end of ramadan (day 27). portions of the serum samples were used immedi...

conclusions it may be concluded that combination of losartan with higher dose of va decreases ischemic markers and lipid peroxidation and augments endogenous antioxidant and hence, protects myocardium against i/r-induced oxidative stress injuries. results there was a more significant decrease in the levels of ldh, cpk, ck-mb, and mda as well as increase in the levels of sod, cat and gpx in grou...

conclusions in conclusion, taking gse for eight weeks had beneficial effects on the plasma gsh, mda levels, and markers of insulin metabolism of female volleyball players. results supplementation with gse resulted in a significant rise in the plasma glutathione (gsh) level (+265.5 ± 344.2 vs. +2.2 ± 378.2 µmol/l, p = 0.02), as well as a significant decrease in the malondialdehyde (mda) level (-...

background: superoxide radicals are produced during oxidative metabolic processes, and removed by superoxide dismutase (sod) enzymes. controversial results have been reported regarding the tissue and plasma concentration of sod in patients with breast cancer. methods: venous blood was obtained from study participants and activity of sod enzyme was determined in 100 women. comparison was made be...

background: the contribution of neuroinflammation in alzheimer’s disease (ad) has been widely reported. the effects of female gonadal hormones in both neuroinflammation and brain cognitive functions have also been well considered. objectives: in the present study, the possible protective role for endogenous ovarian hormones against learning and memory impairment as well as brain tissues oxidati...

background smoking is an established risk factor for cardiovascular diseases and metabolic syndrome. objectives here we aimed to assess the effect of 3-month aerobic training on c-reactive protein (crp) level and total antioxidant capacity (tac) in male smokers. results aerobic training resulted in a significantly increased tac (p < 0.001), but crp remained unchanged (p = 0.96). conclusions des...