Human Chorionic Gonadotrophin (hCG) is mainly a product of the syncytiotropoblastic cells of the placenta although it is also secreted, in lesser quantities, by cytotrophoblastic cells and several nonplacental tissues. It is produced in gestational trophoblastic neoplasms (GTN) and maybe seen in nontrophoblastic neoplasms (Stenman, 2006). hCG is essential in pregnancy as it promotes transformat...

: Mature cystic teratomas (MCTs), also known as dermoid cysts, are the most common ovarian germ cell tumors and neoplasms in patients younger than 20 years. MCTs mainly appear pelvic masses that made up of different types well differentiated derivates at least two germinative types. MCT ovary is always benign lesions with slow growth good prognosis. Unfortunately, about 1–2% cases, it may under...

Available statistics on smoking, alcohol, food supply, reproductive history, and other lifestyle habits from the U.S. and Italy were compared and related to mortality rates of common neoplasms over the period 1955 to 1980. Per capita cigarette consumption has declined in the U.S. since the early 1960s but continues to rise in Italy, chiefly due to the recent increase in cigarette smoking among ...

The accepted view of ovarian carcinogenesis is that carcinoma begins in the ovary, undergoes progressive "dedifferentiation" from a well to a poorly differentiated tumor, and then spreads to the pelvic and abdominal cavities before metastasizing to distant sites. It has therefore been reasoned that survival for this highly lethal disease could be improved by developing screening methods that de...

A new paradigm for the pathogenesis of ovarian cancer has recently been proposed which helps to explain persistent problems in describing the development and diverse morphology of these neoplasms. The paradigm incorporates recent advances in our understanding of the molecular pathogenesis of epithelial 'ovarian' cancer with new insights into the origin of these tumors. Correlated clinicopatholo...

A discussion of the classification of tro­ phoblastic neoplasms with clinical scien­ tists is of importance, for the work of those who direct pathology, biochemistry, en­ docrine and hematology laboratories is essential in the diagnosis and manage­ m ent of these neoplasms. Proper therapy requires the correct histopathologic diag­ nosis, monitoring of marrow, renal and marrow function and, m os...

Breast cancer (C50) and neoplasms of female genital organs (C51-C58) represent one of the most frequent cancer groups among females in economically developed countries. The Institute of Public Health of the Osijek-Baranja County in collaboration with different county institutes provide updated information on the cancer occurrence and trends in the Osijek-Baranja County (OBC). The aim of this ar...

background esophageal, stomach, and colorectal cancers are commonly lethal gastrointestinal tract (git) neoplasms, causing almost two million deaths worldwide each year. some environmental risk factors are acknowledged; however, genetic defects can significantly contribute to predisposition to git cancers. accordingly, recent works have shown that single-nucleotide polymorphisms (snps) within m...

Mucinous tumors may arise from a variety of anatomic locations; however, their clinical behavior varies considerably depending on their origin. When mucinous tumors involve the abdominal cavity, it may lead to mucinous ascites, clinically known as pseudomyxoma peritonei. While most cases are derived from the appendix, it may arise from a mucinous tumor of the ovary. However, the biological pote...

A collision tumor is the coexistence of two distinct tumours without any histological intermixing in same organ or tissue. Each component tumors occurs coincidently and biologic behaviour depends on their own characteristics. 48 year aged P2L2 women with pain abdomen since 15 days, abdominal examination-a cystic mass occupying left iliac fossa present, bimanual examination a measuring 13x10x8 c...