OBJECTIVE To evaluate the diagnostic accuracy of multidetector 64-slice computed tomography (MDCT) in the diagnosis and differentiation of benign and malignant ovarian masses using histopathology and surgical findings as the gold standard. MATERIAL AND METHODS This study was conducted in Aga Khan University Hospital, Karachi, Pakistan. Data was reviewed retrospectively from 1 November 2008 to...

OBJECTIVES To assess the association of adenomyotic foci with co-existing benign ovarian cysts.  METHODS This prospective cross-sectional study consisted of 100 consecutive hysterectomy specimens referred to Histopathology Section of Pathology Department, Peshawar Medical College, Peshawar, Pakistan by its attached teaching hospitals from January 2011 to December 2012. Hematoxylin and eosin s...

OBJECTIVE To assess the performance of contrast-enhanced ultrasound (CE-US) in the differential diagnosis of malignant and benign ovarian tumors. METHODS We conducted a comprehensive literature search of PubMed and EMBASE to identify published articles evaluating the diagnostic potential of CE-US for the differentiation of benign and malignant ovarian tumors. Inclusion criteria were: (1) the ...

Female patients who present with adnexial mass and weight loss should not be presumed to have ovarian carcinoma until after extensive investigation. This is to avoid the mistake of radical surgery with its attendant morbidity and mortality. An important disease to consider in our environment is ovarian TB that respond well to medication. A 35 year old HIV-1 positive house wife presented with fe...

OBJECTIVE Ovarian needle aspiration and biopsy (ONAB) may be employed for pretreatment diagnosis of ovarian malignancies or intraoperatively to facilitate removal of ovarian masses. However, there is reluctance to utilize this procedure due to potential cyst rupture or seeding of malignant cells. The objective of this study was to examine the efficacy of ONAB over a 13-year period at our instit...

The present study was conducted to assess whether imprint cytology can help in rapid diagnosis of ovarian neoplasm and thus facilitate individualized treatment. Aims of our study were to establish the validity and reliability of Imprint cytology in intraoperative diagnosis of ovarian tumour and to compare the significance of cytological diagnosis with histopathological report. Ours is an Instit...

BACKGROUND Malignant transformation in a mature cystic ovarian teratoma is rare. Except in cases with high index of suspicion or overt metastasis, oophorectomy is the mainstay of treatment for ovarian teratoma. METHOD A 46-year-old perimenopausal woman who had salpingo-oophorectomy following a clinical diagnosis of benign ovarian tumour that was subsequently reported histologically as mature ...

BACKGROUND AND OBJECTIVE The objective of this study was to explore whether fluorescence spectroscopy signatures differed between normal variations within the ovary, benign neoplasms, and ovarian cancer. STUDY DESIGN/MATERIALS AND METHODS Ovarian tissue fluorescence emission spectra were collected sequentially at 18 excitation wavelengths ranging from 330 to 500 nm from 11 patients undergoing...

Aims: To investigate whether there is a difference between serum tumor markers panel (CA 125, CA 19-9, 15-3, and carcinoembryonic antigen (CEA)) size histopathology in well-staged patients with borderline ovarian tumors (BOTs). 
 Methods: Over the past 20 years (January 2001 to January 2021), results of four have been clinically analyzed for this retrospective cohort study 156 who underwen...