The purpose of this study was to investigate whether the epidermal growth factor receptor (EGFR) and signal transducer and activator of transcription-3 (STAT3) signal pathway contributes to the carcinogenesis of intrahepatic cholangiocarcinoma (ICC) induced by 3'-methyl-4 dimethylaminoazobenzene (3'Me-DAB) in rats. EGFR, TGFα, STAT3 and p-STAT3 in different stages of carcinogenesis were detecte...

The presence of an oval pupil usually localizes the neurologic problem to the midbrain.

Angular momentum ceases to be the preferred basis for identifying dynamical localization in an oval billiard at large excentricity. We give reasons for this, and comment on the classical phase-space structure that is encoded in the wave functions of “leaky” dielectric resonators with oval cross section. Geometric optics is an important engineering tool because of its explanatory and predictive ...

Given a convex region in the plane, and a sweep-line as a tool, what is best way to reduce the region to a single point by a sequence of sweeps? The problem of sweeping points by orthogonal sweeps was first studied in [2]. Here we consider the following slanted variant of sweeping recently introduced in [1]: In a single sweep, the sweep-line is placed at a start position somewhere in the plane,...

Progressive narrowing of the aortic valve orifice eventually leads to limitations in cardiac output and myocardial blood flow, particularly during exercise or other physiological stress. The pressure gradient across the stenotic aortic valve is a useful and reproducible measure of the severity of the stenosis in most patients. The mainstay of therapy for aortic stenosis is relief of the fixed o...

The temporomandibular joint is one of the most intricate human articulations (TMJ). Each made up a mandibular condyle and its associated temporal cavity (glenoid fossa articular eminence). Human morphology can be divided into six types: Type I: Oval; II: Flattened; III: Diamond; IV: Crooked finger; V:Bifid VI: Bird beak. appears in several different age groups individuals many distinct ways. Co...