UNLABELLED To evaluate the importance of collagen and hydroxyapatite in the regeneration of fractures experimentally induced in the fibulas of rats. METHOD 15 rats were used. These were subjected to surgery to remove a fragment from the fibula. This site then received a graft consisting of a silicone tubes filled with hydroxyapatite and collagen. RESULTS Little bone neoformation occurred in...

Cementless femoral fixation by means of bone ingrowth has been successful in total hip arthroplasty in patients with sufficient bone quality. Consistent bone ingrowth and resultant long-term success involve many factors, including surgical technique, initial mechanical stability achieved at time of implantation, stem design and material, and implant surface. One potential method for achieving f...

Percutaneous vertebral augmentation (VA) and reconstruction with intravertebral polyethylene mesh sac (OptiMesh) and morcelized bone graft provided a minimally invasive efficacious and controlled delivery mechanism to stabilize and treat painful osteoporotic, traumatic and neoplastic vertebral compression fractures (VCFs), as well as avoided serious complications from Polymethylmethacrylate (PM...

A regenerative procedure treating a local osseous defect around titanium dental implant using porous titanium granules is described in four patients. Porous titanium granules represent, for maxillofacial surgery, a new alternative in augmenting osseous defects. Its earliest application was in the field of orthopedics for stabilization of tibia plateau fractures and for reoperations in prostheti...

Filion, T; Li, X; Kreider, JM; Goldstein, SA; Ayers, DC; +Song, J University of Massachusetts Medical School, Worcester, MA; University of Michigan, Ann Arbor, MI +Senior author [email protected]; Filion and Li contributed equally INTRODUCTION: There is a pressing need for the development of more effective strategies to repair critical-sized bony defects in patients who have had volumetric ...

For successful bone tissue engineering, a scaffold needs to be osteoconductive, porous, and biodegradable, thus able to support attachment and proliferation of bone cells and guide bone formation. Recently, hydroxyapatites (HA), a major inorganic component of natural bone, and biodegrade polymers have drawn much attention as bone scaffolds. The present study was designed to investigate whether ...