Clinical translation of cell-based strategies for regenerative medicine demands predictable in vivo performance where the use of sera during in vitro preparation inherently limits the efficacy and reproducibility. Here, we present a bioinspired approach by serum-free pre-conditioning of human periosteum-derived cells, followed by their assembly into microaggregates simultaneously primed with bo...

Besides eradication of chronic middle ear disease, the reconstruction of the sound conduction apparatus is a major goal of modern ear microsurgery. The material of choice in cases of partial ossicular replacement prosthesis is the autogenous ossicle. In the event of more extensive destruction of the ossicular chain diverse alloplastic materials, e. g. metals, ceramics, plastics or composits are...

Cyamella, an accessory sesamoid ossicle of the popliteus in the region of the proximal myotendinous junction, is an extremely unusual finding, with a paucity of current published literature describing its MR appearance. In this case study, we describe MRI findings in a 44-year-old female presenting with pain after a stretching workout. Bone edema in the cyamella, edema in the myotendinous porti...

The authors report a case of direct compression of the medial branch of the deep peroneal nerve by an os intermetatarseum in a 52-year-old female patient who was referred to their Institution because of pain over the dorsum of her left foot associated with paraesthesias in the first web space. Examination disclosed a positive Tinel sign over the dorsal aspect of the first metatarsal bone. Plain...

Cochlear hair cells convert sound vibration into electrical potential, and loss of these cells diminishes auditory function. In response to mechanical stimuli, piezoelectric materials generate electricity, suggesting that they could be used in place of hair cells to create an artificial cochlear epithelium. Here, we report that a piezoelectric membrane generated electrical potentials in respons...

The US-Russian joint quail embryo project was designed to study the effects of microgravity on development of Japanese quail embryos incubated aboard Mir. For this part of the project, eyes from embryonic days 14 and 16 (E14 and E16) flight embryos were compared with eyes from several groups of ground-based control embryos. Measurements were recorded for eye weights; eye, corneal, and scleral r...

This study was conducted to find out the frequency of ossicular chain pathology in cases of tubotympanic chronic suppurative otitis media. This was prospective study, carried out in the department of otorhinolarymgology, NIMS medical college, Jaipur from Jan 2014 to June 2015. One hundred fifty cases of chronic suppurative otitis media, who underwent surgery, were included and their intraoperat...