L1210 murine leukemia cells were treated in vitro with the novel antineoplastic agent 8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d] -1,2,3,5-tetrazin-4(3H)-one (M&B 39565), and its interaction with cellular DNA was assessed by alkaline elution. DNA interstrand cross-link and DNA-protein cross-link formation was quantified with regard to drug concentration and length of incubation time after a 2-h...

This research aimed to investigate the changes in ethical issues in everyday clinical practice recognized by critical care nurses during two observation periods. We conducted a retrospective analysis of data obtained by prospective questionnaire surveys of nurses in the intensive care units (ICU) of a tertiary university-affiliated hospital in Seoul, Korea. Data were collected prospectively dur...

how to cite this article: farhadi r, alaee ar, alipour z, abbaskhanian a, nakhshab m, derakhshanfar h. prevalence of stroke in neonates who admitted with seizures in neonatal intensive care unit. iran j child neurol. autumn 2015;9(4):41-47. abstract objective prevalence of neonatal stroke has been reported 1/2300-1/4000 live births and accounts for 12-20% of the cases of neonatal seizures. alth...

background: the concept of family- centered care in neonatal intensive care unit has changed drastically in protracted years and has been used in various contexts differently. since we require clarity in our understanding, we aimed to analyze this concept. methods: this study was done on the basis of developmental approach of rodgers’s concept analysis. we reviewed the existing literature in sc...

The involvement of inhibitory transmitters for Ptychodiscus brevis toxin (PbTx)-induced depression of spinal synaptic transmission in neonatal rats was investigated. Stimulation of a dorsal root evoked monosynaptic reflex (MSR) and polysynaptic reflex (PSR) potentials in the segmental ventral root. The PbTx depressed the reflexes in a concentration-dependent manner and this depression was block...

protein oxidationm.longissimus dorsi andm. semimembranosuswas studied in ram lambs of northeastern bulgarian fine wool breed and cross of this breed with ile de france, reared and in doors and on pasture.the degree of protein oxidation is determined by measuring the content of carbonyls, formed during the storage of the investigated muscles at low temperatures(4˚с till6thday and -20˚с till90thd...

sareshtedari m 1 (md) , shahamat h 1 (md) , sadeghi t 2 * (msc)       1 department of pediatrics, school of medicine, qazvin university of medical sciences, qazvin, iran   2 department of pediatrics, school of nursing and midwifery, tehran university of medical sciences, tehran, iran     received: 22 jan 2011, accepted: 23 jun 2011       abstract     introduction: regarding the importance of me...

Physicians are key personnel in a sector which is important due to its size as well as the quality of service it provides. We estimate the labor supply of physicians employed at hospitals in Norway, using personnel register data merged with other public records. A dynamic labor supply equation is estimated using a sample of 1303 male physicians observed over the period 1993-1997. The methods of...