The solid state structures of a number of ortho-substituted arylboronic acids, ortho-bromophenyl, ortho-phenylphenyl, pentamethylphenyl, and 10-bromo-9-anthryl, were determined by X-ray diffraction techniques. All boronic acids investigated form dimers in the solid state, but the interconnection of dimers to ribbons differs from that of the parent phenylboronic acid. Pentamethylphenylboronic ac...

Here, we attempt to constrain the propagation length of positrons by a spatial analysis 511-keV line and ortho-positronium (ortho-Ps) continuum in Milky Way bulge from 15 yr INTEGRAL/SPI data. Weidenspointner et al. (2006) reconstructed an image energy band 410–500 keV, where ortho-Ps is dominant, found asymmetric component. For first time, perform spectrally resolved study that extends lower e...

In vitro fertilization (IVF) with reception of oocytes from partners (ROPA) allows lesbian mothers to share biological motherhood. The gestational mother receives an egg from her partner who becomes the genetic mother. This article examines the ethics of IVF with ROPA with a focus on the welfare of the woman and the resulting child, on whether ROPA qualifies as a "legitimate" medical therapy th...

Genetic engineering is a powerful means of accclcrating the evolution of new biological activities and has coDsiderable potential for constructing microorganisms that can degrade environmental poUutants. Critical enzymes from five different catabolic pathways of three distinct soil bacteria have been combined in patq,.work fashion into a functional ortbo cleavage route for the degradation of me...

A base-promoted one-pot tandem reaction sequence has been developed to transform electron-deficient chromone-fused dienes 1 and 1,3-dicarbonyl compounds 2 to functionalized 2-hydroxybenzophenones 3 under mild conditions. This domino process, which involves multiple reactions, including Michael addition/cyclization/elimination, serves as an efficient, economic, and eco-friendly method for the co...

Increasing the number of meso-methine carbons porphyrin has led to a creation series vinylogous expanded porphyrins, while introduction an ortho-phenylene-unit as pyrrole-connecting two-carbon bridge usually leads prevention effective macrocyclic conjugation. Cyclopentene can serve conjugative increase conjugation owing its cis-geometry. In this work, ortho-phenylene-cyclopentene-bridged tetrap...

The regioselectivity of deprotonation reactions between arene substrates and basic metalating agents is usually governed by the electronic and/or coordinative characteristics of a directing group attached to the benzene ring. Generally, the reaction takes place in the ortho position, adjacent to the substituent. Here, we introduce a protocol by which the metalating agent, a disodium-monomagnesi...

A solvent-free palladium-catalyzed ortho-iodination of acetanilides using N-iodosuccinimide as the iodine source has been developed under ball-milling conditions. This present method avoids the use of hazardous organic solvents, high reaction temperature, and long reaction time and provides a highly efficient methodology to realize the regioselective functionalization of acetanilides in yields ...

The coupling of ortho- and para-phenols with secondary and tertiary boronic esters has been explored. In the case of para-substituted phenols, after reaction of a dilithio phenolate species with a boronic ester, treatment with Ph3 BiF2 or Martin's sulfurane gave the coupled product with complete enantiospecificity. The methodology was applied to the synthesis of the broad spectrum antibacterial...

A very efficient electrogenerated Fe(0) porphyrin catalyst was obtained by substituting in tetraphenylporphyrin two of the opposite phenyl rings by ortho-, ortho'-phenol groups while the other two are perfluorinated. It proves to be an excellent catalyst of the CO2-to-CO conversion as to selectivity (the CO faradaic yield is nearly quantitative), overpotential, and turnover frequency. Benchmark...