This study pertains to eighty six suicide attempters. The findings indicated that in both sexes the peak age group was 15 - 20 years, followed by 21 - 25 years. Organophosphorous compounds were found to have been used by a large number of attempters. 23.25% of our sample had contemplated on this act even prior to this episode. Alcohol was found to be an important factor behind 10.46% of cases. ...

Fenitrothion (Sumithion), and organophosphorous insectide, was applied dermally to rats. Cholinesterase activity was measured in blood and brain. The concentration of the pesticide in blood plasma and acetylcholine in brain were estimated at different intervals. The maximum concentration of Fenitrothion in the plasma was found at 4 hrs while significantly elevated levels of acetylcholine were p...

Organophosphorous compounds are involved in many toxic compounds such as fungicides, pesticides, or chemical warfare nerve agents. The understanding of the decomposition chemistry of these compounds in the environment is largely limited by the scarcity of thermochemical data. Because of the high toxicity of many of these molecules, experimental determination of their thermochemical properties i...

Chlorpyrifos is a broad spectrum moderately toxic organophosphorous insecticide. It is widely used in agriculture for pest control and in households as a termicide. However, exposure to chlorpyrifos and its metabolites can affect the public health resulting from its long residual periods in soil and water. Thus, there is an essential need to develop sensitive method for the detection of chlorpy...

Cancer progression has been associated with an increase in genomic instability indicated by inactivation of tumor suppressor genes and activation of oncogenes. Epidemiological and experimental evidence has implicated estrogens in the etiology of breast cancer. To study environmental organophosphorous pesticides is of interest since evidence indicate that pesticides may enhance cell division, in...

Organophosphorus compounds have been used as pesticides and as chemical warfare nerve agents. The mechanism of toxicity of organophosphorus compounds is the inhibition of acetylcholinesterase, which results in accumulation of acetylcholine and the continued stimulation of acetylcholine receptors. Therefore, they are also called anticholinesterase agents. Organophosphorus pesticides have largely...