OBJECTIVE The physical examination of peripheral perfusion based on touching the skin or measuring capillary refill time has been related to the prognosis of patients with circulatory shock. It is unclear, however, whether monitoring peripheral perfusion after initial resuscitation still provides information on morbidity in critically ill patients. Therefore, we investigated whether subjective ...

Cyclophosphamide is one of the chemotherapeutics for cancer, however this drug has severe side effects in multiple organs and a well-known mutagenic agent. In work protective activity antioxidant-rich Carob (Ceratonia siliqua L.) pods leaves extracts against cyclophosphamide induced genotoxicity was studied. Safety these evaluated acute subacute toxicity tests at dose 1500 mg/kg/day albino rats...

the human mdr1 gene encodes for a p-glycoprotein (pgp), which acts as an efflux pump that transports a large variety of substrates from the inside of cells to the outside until protection against xenobiotics. the g2677t/a polymorphism in exon 21 is associated with pgp expression and function in humans. the present study was aimed to determine the frequencies of this polymorphism in a healthy po...

Dosimetry system for measuring organ doses of the patients undergoing clinical x-ray examinations was devised by using newly developed photodiode dosimeters installed in an anthropomorphic phantom realizing standard Japanese adult body. The system was constructed using pin silicon photodiode dosimeters, 32 and extra two in number, inserted at the positions of tissues or organs assigned in the I...

in order to examine the effect of the quantity of nitrogen fertilizer and bush density on vegetative and productive function of henna medicinal plant (lawsonia inermis)  factorial experimentation in the form of block plan was carried in three stages in agriculture research center in south of kerman  province in corp of 2012. the first factor containing nitrogen fertilizer in 4 levels including ...

background: pet/ct imaging using [18f]-fdg is utilized in clinical oncology for tumor detecting, staging and responding to therapy procedures. essential consideration must be taken for radiation staff due to high gamma radiation in pet/ct and cyclotron center. the aim of this study was to assess the staff exposure regarding whole body and organ dose and to evaluate environment dose in pet/ct an...

Background: This study aimed to estimate and compare the absorbed dose, lifetime cancer risk and mortalities due to cone-beam computed tomography (CBCT) and panoramic examinations on patients. Materials and Methods: The exposure factors were applied to 332 patients in two age groups (6-10, and ˃18-year-old). The dose-area product (DAP) values were measured for CBCT and panoramic radiographies. ...

Abstract Background A Phase 1, single center study is ongoing to evaluate the conditionally replicative oncolytic adenovirus, DNX-2401 (tasadenoturev), followed by radiotherapy (RT) in pediatric patients with newly diagnosed diffuse intrinsic pontine glioma (DIPG). Methods Patients 1–18 years DIPG no prior treatment, Lansky/Karnofsky performance score ≥ 70, and adequate organ function were enro...

As we know breast cancer is the second death reason in Iran. One step of treatment process is radiotherapy, which needs careful consideration of contouring and therapeutic techniques Lung, thyroid, spinal cord, trachea and humerus are sensitive organs in breast cancer radiation therapy.  The most clinical studies recommended two ways for delivering 95 percent of dose to supraclavicular and ...