Introduction: The aim of this study was to evaluate the human organ absorbed dose of [111In]In-DTPA-antiMUC1, as a newly developed radioimmunoconjugate. Methods: [111In]In-DTPA-antiMUC1 was prepared at optimized conditions while the radiochemical purity of the tracer was investigated using ITLC method. Biodistribution of the radiolab...

Introduction:The use of beta emitters is one of the effective methods for palliation of bone metastasis. The risk of normal tissue toxicity should be evaluated in the bone pain palliation treatment. Methods: In this study, the Monte Carlo simulation code MCNPX was used for simulation a bone phantom model consisted of bone marrow, bone and soft tissue. Spe...

Background: PET/CT imaging using [18F]-FDG is utilized in clinical oncology for tumor detecting, staging and responding to therapy procedures. Essential consideration must be taken for radiation staff due to high gamma radiation in PET/CT and cyclotron center. The aim of this study was to assess the staff exposure regarding whole body and organ dose and to evaluate environment dose in PET/CT an...

The present study was designed to investigate the effects of low-dose ketanserin on BPV (blood pressure variability), BRS (baroreflex sensitivity) and organ damage in SHR (spontaneously hypertensive rats). Ketanserin was mixed in rat chow at an estimated dose of 0.1 mg.kg(-1) of body weight.day(-1). SHR were treated for 4 months. BP (blood pressure) was then recorded continuously for 24 h in a ...

BACKGROUND To investigate the organ dose, effective dose (ED), conversion factor, and the C-arm rotation angle effects on dose variations of abdominal C-arm cone-beam computed tomography (CBCT) during transarterial chemoembolization (TACE). METHODS The organ doses and EDs for abdominal C-arm CBCT were retrospectively calculated according to a Monte Carlo technique for 80 patients. Dose variat...

We modified the Imaging Performance Assessment of CT scanners (ImPACT) to evaluate the organ doses and the effective dose based on the International Commission on Radiological Protection (ICRP) Publication 110 reference male/female phantom with the Aquilion ONE ViSION Edition scanner. To select the new CT scanner, the measurement results of the CTDI100,c and CTDI100,p for the 160 (head) and the...

Abstract Purpose In this work, we address image segmentation in the scope of dosimetry using deep learning and make three main contributions: (a) to extend optimize architecture an existing convolutional neural network (CNN) order obtain a fast, robust accurate computed tomography (CT)-based organ method for kidneys livers; (b) train CNN with inhomogeneous set CT scans validate daily dosimetry;...

The distribution of radiation doses in cancer patients who receive radiotherapy treatment depends on the distance cancerous organ to source, type including density and atoms organ. Even though exposure is focused that will be irradiated, surrounding healthy organs still have a great chance getting exposure. Healthy can exposed within certain period time are thought opportunity experience metast...

Purpose To compare patient radiation doses in cone beam computed tomography (CBCT) of two mobile systems used for navigation-assisted mini-invasive orthopedic surgery: O-arm®O2 and Surgivisio®. Methods The study focused on imaging the spine. Thermoluminescent dosimeters were to measure organs effective (ED) during CBCT. An ionization-chamber a solid-state sensor incident air-kerma (Ki) at cente...