Oral Squamous Cell Carcinoma (OSCC) is the most frequent oral cancer. The management for OSCC are surgery, chemotherapy, and radiotherapy. Chemotherapy radiotherapy have high toxicity side effects, therefore effort needed to reduce them. Several studies show that herbal medicines anticancer effects with lower effects. objective discuss about of using chemotherapy as adjunctive therapy. A 59-yea...

Back Ground:The most important prognostic factor for squamous cell carcinoma (SCC) of oral is the status cervical lymph nodes. Cure rates drop by 50% with involvement regional nodes.The rate occult metastasis in clinically negative neck tongue cancers ranges from <20% to >30% depending on many predictors. Methods:The relationship clinical and histologic features primary tumor nodes was in...

  Tongue base lesions have a diverse and extensive etiology. One of the benign tongue base lesions is schwannoma. Schwannoma and neurofibroma are two tumors of the peripheral nerves originating in the nerve sheaths. Schwannoma account for just over 1% of benign tumors which have been reported in the ora...

INTRODUCTION In oral cavity, the tongue is the most common site prone to development of squamous cell carcinoma (SCC). Considering malignant transformation as a cellular stress, the expression of heat shock proteins (HSPs) may be affected in this process. In this study we assessed the expression of HSP105 and HSP27 as two of the most interested stress proteins and investigated their relationshi...

Pseudoepitheliomatous hyperplasia (PEH) is a histopathological reaction pattern to various stimuli, which includes trauma, infection, inflammation, neoplasia. It is seen as tongue like epithelial proliferation invading the connective tissue and should not be mistaken for squamous cell carcinoma (SCC). This review enlists oral lesions which exhibit PEH with a note on how to differentiate SCC fro...

Objectives: To determine whether, in a developing world context, early oral feeding after laryngectomy is safe, cost-effective and appropriate. Study design: A prospective study of early oral feeding after laryngectomy, compared with retrospective, historical delayed feeding controls. Method: Forty patients underwent total laryngectomy for advanced carcinoma of the larynx with or without hypoph...

Background: Malignancies of tongue represent one of the greatest management challenges for the head and neck oncologists because of the adverse effects of treatment on oral and pharyngeal functions. Diagnosis at later stages results in poor treatment outcomes and considerable costs to patients. Bioelectric impedance analysis (BIA)-derived phase angle offers an emerging opportunity to assess pro...

introduction: granular cell tumors (gcts) are rare and mostly benign soft tissue tumors. though they have been reported in all parts of body, they are generally located in the head and neck region, especially on the tongue. some malign forms exist, but these have been rarely reported. granular cell tumors have a neural origin and, in immunohistochemical evaluations, they express s-100 and neuro...

BACKGROUND Only few studies on tongue lesions considered sizable populations, and contemporary literature does not provide a valid report regarding the epidemiology of tongue lesions within the Italian population. In this report, the histopathological and clinical appearance of 1.106 tongue lesions from northern Italians are described and discussed. MATERIAL AND METHODS The case records of pa...