Graft-vs-host disease is still the leading cause of morbidity and mortality in patients undergoing bone marrow transplantation. It is important to start treatment early to reduce the severity and consequences of this complication. Cutaneous lesions are often the presenting compliant of graft-vs-host disease and presage visceral involvement. We present the case of a 45-year-old woman with multip...

This is a case report of an oral lichenoid drug reaction of the buccal sulci in a female diabetic patient who was on an anti-hypertensive drug, alpha-methyldopa (Aldomet) and an oral hypoglycaemic drug, chlorpropamide (Diabinese). The clinical features, histological findings and management are presented.

BACKGROUND Palladium (Pd) and gold (Au) based dental alloys have been associated with oral disease. OBJECTIVES This study was designed to explore possible associations between the presence of Au-based and Pd-based dental alloys, and oral lesions, systemic complaints, and specific in vivo and in vitro immune responses. METHODS The investigated population consisted of three groups: 26 non-met...

The presence of numerous acquired comedones on the trunk and limbs of an adult patient, with no other family member affected and with no triggering factors to explain their presence, requires us to rule out those conditions in which comedones are the predominant clinical feature. The fact that these lesions appear in association with areas of lichen ruber planus presents the dilemma of whether ...

A 34 year man presented to us with itchy lesions on one half of the trunk for the past two months. The lesions started as erythematous to violaceous papules and plaques on the flank and gradually increased in number to involve the left side of the trunk (Figure 1 and 2). Some areas showed the Koebner phenomenon. These lesions were distributed along the lines of Blaschko. Examination of the oral...

Oral postinflammatory pigmentation (OPP) is a discoloration of the oral mucosa caused by an excess of melanin production and deposition within the basal layer of the epithelium and connective tissue of areas affected by chronic inflammation. Therefore, it is mandatory to demonstrate the association with a previous or concomitant inflammatory process in the same area of oral mucosa. Clinically O...

Leishmaniasis is a infectious disease with broad spectrum of clinical features from typical noduloulcerative lesion to atypical lesions. In this article, we presented 4 cases with atypical presentation of cutaneous leishmaniasis lesions (including eczematous, sporotrichoid and lichenoid) in an endemic area in Iran, Kerman. The first case was a 28- year- old man presented with a pruritic purplis...

Lichenoid reaction is a mucosal lesion characterized by linear whitish striae appearing on the mucosa and is triggered by external factors like restorative materials, betel nut, tobacco, graft versus host reaction and drugs. A detailed history will help in delineating the two lesions. The review provides an insight into the clinical, histological features and the malignant potential of Lichenoi...

Oral lichen planus (OLP) and oral lichenoid lesions (OLL) are clinically and histologically similar lesions but their treatment planning and prognosis are different. The review of the literature indicates numerous criteria to distinguish these two lesions; however there is a lot of inconsistency. Thus, the aim of this study was to determine the correlation of histopathology and clinical OLP and...