The colon targeted drug delivery system has a number of important implications in the field of pharmacotherapy. Oral colon targeted drug delivery system has recently gained importance for delivering a variety of therapeutic agents for both local and systemic administration targeting of drugs to the colon via oral administration protect the drug from degradation or release in the stomach and sma...

The colon targeted drug delivery system has a number of important implications in the field of pharmacotherapy. Oral colon targeted drug delivery system has recently gained importance for delivering a variety of therapeutic agents for both local and systemic administration Targeting of drugs to the colon via oral administration protect the drug from degradation or release in the stomach and sma...

The colon targeted drug delivery system has a number of important implications in the field of pharmacotherapy. Oral colon targeted drug delivery system has recently gained importance for delivering a variety of therapeutic agents for both local and systemic administration targeting of drugs to the colon via oral administration protect the drug from degradation or release in the stomach and sma...

Administration of drug by oral route is the most effective and acceptable route as it has better therapeutic efficacy, low cost and good patient compliance. More than 40% of new drugs are poorly water soluble. These drugs present development challenges and also have poor bioavailability. Although many formulation approaches like solid dispersions, complexation, pH modification exist, novel lipi...

The purpose of present investigation was to achieve successful delivery especially to colon using microbially triggered, osmotically controlled approach. Prednisolone was chosen model drug for treatment of inflammatory bowel disease (IBD). Prednisolone-β-cyclodextrin complex were prepared and phase solubility study was carried out. Cellulose acetate solution containing chitosan was used to prep...

Among novel drug delivery systems, Buccal mucoadhesive systems have attracted great attention in recent years due to their ability to adhere and remain on the oral mucosa and to release their drug content gradually. Mucoadhesion may be defined as the process where polymers attach to biological substrate or a synthetic or natural macromolecule, to mucus or an epithelial surface. Buccal mucoadhes...

the purpose of this review article is to characterize all of the parameters regarding the types, polymers used, and release kinetics of matrix tablets. matrix system was the earliest oral extended release platform for medicinal use. matrix tablets are most commonly used methods to modulate the release profile of drugs. they are much desirable and preferred for such therapy because they offer be...

Background: Intravenous drug delivery is an advantageous choice for rapid administration, immediate drug effect, and avoidance of first-pass metabolism in oral drug delivery. In this study, the synthesis, formulation, and characterization of atorvastatin-loaded polyurethane (PU) nanoparticles were investigated for intravenous route of administration. Method: First, PU was synthesized and charac...